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Case Reports
. 2023 Sep;24(3):352-355.
doi: 10.30476/dentjods.2023.96208.1927.

Epithelioid Hemangioendothelioma of Tongue: A Rare Presentation

Affiliations
Case Reports

Epithelioid Hemangioendothelioma of Tongue: A Rare Presentation

Durga Bai Yendluri et al. J Dent (Shiraz). 2023 Sep.

Abstract

Hemangioendothelioma is a diverse set of proliferative and neoplastic vascular lesions with biological characteristics that fall halfway between benign hemangioma and malignant angiosarcoma. Hemangioendothelioma of the oral cavity is extremely rare and if present, it is seen on lips, gingiva, tongue, maxilla, and mandible. The following case report is about a lesion on the right ventrolateral border of the tongue of a six-year-old female patient. A Laser excision was done. Histopathology revealed the features of hemangioendothelioma. An immunohistochemical (IHC) study was done to correlate the findings with a histopathological picture and arrived at the final diagnosis of epithelioid hemangioendothelioma (EHE). The patient was followed up for two years and no recurrence was noticed.

Keywords: Epithelioid hemangioendothelium; Hemangioendothelioma; Immunohistochemistry; Tongue.

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Conflict of interest statement

The authors declare that they have no conflicts of interests.

Figures

Figure 1
Figure 1
a: Lesion on the right ventrolateral surface of the tongue, b: Immediately after excision
Figure 2
Figure 2
Histological examination showed nests of cells surrounding irregular vascular channels (a: H&E stain) with spindling and hyperchromatism (b: H&E stain), c: Immunohistochemical staining- Positive tumor cells cytoplasmic reaction for d: CD 31 and CD 34
Figure 3
Figure 3
Follow-up at 2 years

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