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. 2023 Dec;39(12):1243-1244.
doi: 10.1002/kjm2.12760. Epub 2023 Sep 20.

Isolated lung involvement in IgG4-related disease

Affiliations

Isolated lung involvement in IgG4-related disease

Nien Ting Lo et al. Kaohsiung J Med Sci. 2023 Dec.
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

FIGURE 1
FIGURE 1
(A) Chest computed tomography showed a nodule with calcified flecks abutting pulmonary lung cyst (yellow box) at the left upper lobe of the lung. (B) Macroscopic appearance of left upper lobe wedge specimen, with blurred margins of a pseudotumor (yellow arrows). (C and D) Section showing a dense infiltration of lymphoplasmacytic cells and storiform fibrosis. (E) Immunohistochemistry showing CD138 staining of plasma cells. (F and G) An increased number of Immunoglobulin G (IgG) plasma cells with IgG4 of 155 per high power field (HPF) as depicted. Ratio of IgG4/IgG is estimated at around 55%.

References

    1. Wallace ZS, Naden RP, Chari S, Choi HK, Della‐Torre E, Dicaire JF, et al. The 2019 American College of Rheumatology/European league against rheumatism classification criteria for IgG4‐related disease. Ann Rheum Dis. 2020;79(1):77–87. - PubMed
    1. Umehara H, Okazaki K, Kawa S, Takahashi H, Goto H, Matsui S, et al. The 2020 revised comprehensive diagnostic (RCD) criteria for IgG4‐RD. Mod Rheumatol. 2021;31(3):529–533. - PubMed
    1. Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, Yoshino T, et al. Consensus statement on the pathology of IgG4‐related disease. Mod Pathol. 2012;25(9):1181–1192. - PubMed
    1. Chen LYC, Mattman A, Seidman MA, Carruthers MN. IgG4‐related disease: what a hematologist needs to know. Haematologica. 2019;104(3):444–455. - PMC - PubMed
    1. Muller R, Ebbo M, Habert P, Daniel L, Briantais A, Chanez P, et al. Thoracic manifestations of IgG4‐related disease. Respirology. 2023;28(2):120–131. - PMC - PubMed