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Meta-Analysis
. 2024 Feb;281(2):537-545.
doi: 10.1007/s00405-023-08242-z. Epub 2023 Sep 20.

Effectiveness of temperature-controlled radiofrequency neurolysis of the posterior nasal nerve to treat chronic rhinitis: a systematic review and meta-analysis

Do Hyun Kim  1 , Soo Whan Kim  1 , Sung Won Kim  1 , Gulnaz Stybayeva  2 , Se Hwan Hwang  3
Affiliations
Meta-Analysis

Effectiveness of temperature-controlled radiofrequency neurolysis of the posterior nasal nerve to treat chronic rhinitis: a systematic review and meta-analysis

Do Hyun Kim et al. Eur Arch Otorhinolaryngol. 2024 Feb.

Abstract

Purpose: This systematic review and meta-analysis evaluates the effect of TRNP on rhinitis-related symptoms.

Methods: We reviewed studies retrieved from PubMed, SCOPUS, Embase, the Web of Science, and the Cochrane database to June 2023. Studies that evaluated quality-of-life and rhinitis-related symptom scores before and after treatment were analyzed, as was one sham-treatment-controlled study.

Results: In total, 406 patients evaluated in five studies were analyzed. TRNP significantly improved rhinitis-related symptoms-congestion, itching, rhinorrhea, and sneezing-for up to 12 months after treatment, compared to before treatment. The most significant symptom decreases were those of rhinorrhea and nasal congestion. Rhinitis-related symptoms had improved significantly at 3 months after TRNP, compared to sham surgery. TRNP improved disease-specific quality-of-life scores on the Rhinoconjunctivitis Quality of Life Questionnaire at 6 months after treatment, compared to before treatment. The rates of clinical improvement in terms of all nasal symptoms (reduction > 30% from baseline) and in quality of life (minimal clinically important difference > 0.4) after TRNP were 79% and 84% respectively. There was no severe adverse event associated with either device use or the overall procedure.

Conclusions: TRNP treatment improved subjective symptoms related to rhinitis, especially rhinorrhea and nasal congestion, and also improved disease-specific quality-of-life scores.

Keywords: Equipment and supplies; Meta-analysis; Nose; Quality of life; Rhinitis.

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