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Case Reports
. 2023 Sep 16;11(26):6311-6317.
doi: 10.12998/wjcc.v11.i26.6311.

Delayed diagnosis of abdominal Henoch-Schonlein purpura in children: A case report

Hui Guo  1 , Zhi-Ling Wang  2 , Zhu Tao  2
Affiliations
Case Reports

Delayed diagnosis of abdominal Henoch-Schonlein purpura in children: A case report

Hui Guo et al. World J Clin Cases. .

Abstract

Background: For children with abdominal Henoch-Schonlein purpura presenting abdominal pain as an initial symptom and severe clinical manifestations, but without purpura appearance on the skin, the diagnosis and treatment are relatively difficult. This study summarized the characteristics of this group of patients by literature review and provided additional references for further refinement of glucocorticoid therapy in this vasculitis.

Case summary: A 6-year-old girl presented mainly with repeated abdominal pain and had received short-term out-of-hospital treatment with hydrocortisone. On day 7 after onset, gastroscopy revealed chronic non-atrophic gastritis and erosive duodenitis without purpuric rash, and no obvious resolution of the abdominal pain was found after treatment against infection and for protection of gastric mucosa. On day 14 the inflammatory indices continued to rise and the pain was relieved after enhanced anti-infective therapy, but without complete resolution. On day 19, the patient presented with aggravated abdominal pain with purplish-red dots on the lower limbs, by which Henoch-Schonlein purpura was confirmed. After 5 d of sequential treatment with methylprednisolone and prednisone, abdominal pain disappeared and she was discharged.

Conclusion: Henoch-Schonlein purpura-related rash may appear after long-term abdominal pain, and should be distinguished from acute and chronic gastrointestinal diseases at the early stage without typical rash. For bacterial infection-induced Henoch-Schonlein purpura, glucocorticoid therapy alone without clearing the infection may not relieve symptoms.

Keywords: Abdominal pain; Case report; Delayed diagnosis; Gastrointestinal disease; Henoch-Schonlein purpura; Rash.

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Conflict of interest statement

Conflict-of-interest statement: All the authors declare that they have no conflict of interest to disclose.

Figures

Figure 1
Figure 1
Gastroscopy and other symptoms. A and B: Gastroscopy images of the child on the 7th (A) and 17th (B) days after the onset (arrows); C: On the 19th day after the onset, purplish-red hemorrhagic dots appeared on the skin of the child's lower limbs (arrows).
See this image and copyright information in PMC

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