Soluble oligomers or insoluble fibrils? Scientific commentary on "Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau"

Affiliations

¹ Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, 60 Fenwood Road, 10002S, Boston, MA, 02115, USA. astern@bwh.harvard.edu.
² Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, 60 Fenwood Road, 10002S, Boston, MA, 02115, USA. dselkoe@bwh.harvard.edu.

Comment

Andrew M Stern et al. Acta Neuropathol. 2023 Dec.

. 2023 Dec;146(6):861-862.

doi: 10.1007/s00401-023-02633-6. Epub 2023 Sep 21.

¹ Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, 60 Fenwood Road, 10002S, Boston, MA, 02115, USA. astern@bwh.harvard.edu.
² Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, 60 Fenwood Road, 10002S, Boston, MA, 02115, USA. dselkoe@bwh.harvard.edu.

No abstract available

Comment in

Reply: Soluble oligomers or insoluble fibrils?
Mate de Gerando A, Quittot N, Frosch MP, Hyman BT. Mate de Gerando A, et al. Acta Neuropathol. 2023 Dec;146(6):863-866. doi: 10.1007/s00401-023-02634-5. Epub 2023 Sep 21. Acta Neuropathol. 2023. PMID: 37733036 Free PMC article. No abstract available.

Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau.
Mate De Gerando A, Welikovitch LA, Khasnavis A, Commins C, Glynn C, Chun JE, Perbet R, Hyman BT. Mate De Gerando A, et al. Acta Neuropathol. 2023 Aug;146(2):191-210. doi: 10.1007/s00401-023-02600-1. Epub 2023 Jun 21. Acta Neuropathol. 2023. PMID: 37341831 Free PMC article.

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