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. 2023 Sep 21;23(1):287.
doi: 10.1186/s12893-023-02183-4.

Incidence of appendiceal neoplasms in appendectomy patients

Ricardo E Núñez-Rocha  1   2 , Felipe Girón  3   4 , Lina Rodríguez  2 , Daniela Camargo-Gómez  2 , Carolina Restrepo-Bonilla  5 , Rocío Del Pilar López Panqueva  1   2 , Manuel Cadena  1   2 , Ricardo Nassar  1   2 , Gabriel E Herrera-Almario  1   2 , Juan David Hernández-Restrepo  1   2
Affiliations

Incidence of appendiceal neoplasms in appendectomy patients

Ricardo E Núñez-Rocha et al. BMC Surg. .

Abstract

Background: Non-operative management has been suggested as a therapy for uncomplicated appendicitis. Notwithstanding, the risk of missing an appendiceal tumor must be considered, being the surgical piece crucial to rule out neoplasms. Therefore, we aim to determine the incidence of appendiceal neoplasms in patients with acute appendicitis, tumor types and the importance of the anatomopathological study of the surgical piece.

Study design: Retrospective study in which we described patients who underwent emergent appendectomy with histopathological findings of appendiceal neoplasms from January 2012 to September 2018. Descriptive analysis included demographic variables, diagnostic methods, and surgical techniques.

Results: 2993 patients diagnosed with acute appendicitis who underwent an emergency appendectomy. 64 neoplasms of the appendix were found with an incidence of 2,14%. 67.2% were women, the mean age was 46,4 years (± 19.5). The most frequent appendiceal neoplasms were neuroendocrine tumors (42,2%), followed by appendiceal mucinous neoplasms (35,9%), sessile serrated adenomas (18,8%), and adenocarcinomas (3,1%). In 89,1% of the cases, acute appendicitis was determined by imaging, and 14% of cases were suspected intraoperatively. Appendectomy was performed in 78,1% without additional procedures.

Conclusions: Appendiceal tumors are rare and must be ruled out in patients with suspected acute appendicitis. The incidence of incidental neoplasms is higher in this study than in the previously reported series. This information must be included in decision-making when considering treatment options for acute appendicitis.

Keywords: Appendectomy; Appendiceal mucinous neoplasms; Appendiceal neoplasms; Appendicitis; Neuroendocrine tumor; Sessile serrated adenomas.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Distribution of appendiceal neoplasms by sex
Fig. 2
Fig. 2
Distribution of appendiceal neoplasms per year
See this image and copyright information in PMC

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