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. 2023 Sep 6:10:1217148.
doi: 10.3389/fcvm.2023.1217148. eCollection 2023.

Surgical treatment of left-sided infective endocarditis with symptomatic neurological complications before surgery in China

Jing-Bin Huang  1 , Chang-Chao Lu  1 , Zhao-Ke Wen  1 , Jian-Rong Yang  1 , Jun-Jun Li  1
Affiliations

Surgical treatment of left-sided infective endocarditis with symptomatic neurological complications before surgery in China

Jing-Bin Huang et al. Front Cardiovasc Med. .

Abstract

Introduction: We aimed to investigate surgical treatment of left-sided infective endocarditis with symptomatic neurological complications before surgery.

Methods: This was a retrospective study of patients with left-sided infective endocarditis and symptomatic neurological complications before surgery undergoing cardiac surgery between January 2006 and November 2022 at our hospital.

Results: Eight hundred thirty-two patients were divided into group with symptomatic neurological complications before surgery (n = 112) and without symptomatic neurological complications before surgery (n = 720). There were 48 operative deaths (5.4%). Univariate and multivariate analyses showed that symptomatic neurological complications before surgery is statistically significantly associated with in-hospital mortality following cardiac surgery and prolonged intubation time.

Conclusions: Our study showed that symptomatic neurological complications before surgery are associated with increased in-hospital mortality following cardiac surgery and prolonged intubation time.

Keywords: left-sided infective endocarditis; mortality; neurological complications before surgery; prolonged intubation time; surgery.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Flow chart of clinical trial.
Figure 2
Figure 2
Kaplan-Meier curve for survival. The follow-up of 750 patients was completed (95.7%, 750/784). Eighty-seven deaths (11.6%, 87/750) occurred within 12 months after being discharged from our hospital because of recurrence of IE and cerebral hemorrhage.
See this image and copyright information in PMC

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