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Case Reports
. 2022 Dec;8(4):32-36.
doi: 10.32598/CMM.2023.1323.

Aspergillus fumigatus cerebral abscess following hemodialysis: A case report

Tanu Sagar  1 , Lata Sheoran  1 , Ajay Prajapati  2 , Bembem Khuraijam  3 , Partha Pratin Jana  1 , P N Pandey  2 , Sonal Saxena  1
Affiliations
Case Reports

Aspergillus fumigatus cerebral abscess following hemodialysis: A case report

Tanu Sagar et al. Curr Med Mycol. 2022 Dec.

Abstract

Background and purpose: Cerebral aspergillosis is a notorious disease that causes rapid clinical deterioration and carries a poor prognosis. Therefore, it requires timely diagnosis and prompt management.

Case report: This study reports a case of fungal cerebral abscess in a 26years old man following hemodialysis,2 months afterdengue-induced acute kidney disease. Aspergillus fumigatus was recovered from a brain abscess specimen that was subjected to a parietal craniotomy. The patient was successfully treated with oral Voriconazole 400mg BD for 2 days, followed by 200 mg BD for 3months.

Conclusion: Hemodialysis patients are at high risk offungal infections due to the frequent use of catheters or the insertion of needles to access the bloodstream. Therefore, a high index of suspicion of fungal infection is required in patients with hemodialysis by the clinician for early diagnosis and treatment.

Keywords: Cerebral abscess; Hemodialysis; Aspergillus fumigatus.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Magnetic resonance imagingscan showing multiple ring enhancement lesions
Figure 2
Figure 2
Intra-operative view of the cerebral abscess
Figure 3
Figure 3
Potassium hydroxide mountshowing hyaline fungal septate hyphae
Figure 4
Figure 4
Giemsa stain showing inflammatory cells with septate hyphae
Figure 5
Figure 5
Grocott’s methenamine silver stain illustrates septate hyphae branching at acute angles
Figure 6
Figure 6
Lacto-phenol cotton bluemount showing Aspergillus fumigatus
See this image and copyright information in PMC

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