Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Dec;58(12):3596-3599.
doi: 10.1002/ppul.26700. Epub 2023 Sep 22.

Pediatric negative pressure pulmonary edema: Case series and review of the literature

Yael Ben-David  1   2 , Lea Bentur  1   2 , Michal Gur  1   2 , Anat Ilivitzki  2   3 , Yazeed Toukan  1   2 , Vered Nir  1   2 , George Shallufi  1 , Husein Dabbah  4   5 , Ronen Bar-Yoseph  1   2
Affiliations
Review

Pediatric negative pressure pulmonary edema: Case series and review of the literature

Yael Ben-David et al. Pediatr Pulmonol. 2023 Dec.

Abstract

Introduction: Negative pressure pulmonary edema (NPPE) is a potentially life-threatening complication that develops rapidly following acute upper airway obstruction. The condition is rare, dramatic but resolves quickly. Prompt recognition and appropriate supportive treatment may prevent unnecessary investigations and iatrogenic complications.

Methods: We describe a spectrum of etiologies and clinical manifestation of pediatric NPPE in our center and review of previous publications.

Conclusion: The etiology for the development of NPPE in children has shifted over the years. Although dramatic in presentation, this type of pulmonary edema often resolves quickly with minimal support.

Keywords: negative pressure pulmonary edema; post-obstruction edema; strangulation; upper airway obstruction.

PubMed Disclaimer

References

REFERENCES

    1. Toukan Y, Gur M, Bentur L. Negative pressure pulmonary edema following choking on a cookie. Pediatr Pulmonol. 2016;51(7):E25-E27.
    1. Toukan Y, Gur M, Keshet D, Bentur L. Negative pressure pulmonary edema in a child following laryngospasm triggered by a laryngeal mask. The Israel Med Association J: IMAJ. 2019;21(1):56-57.
    1. Bhattacharya M, Kallet RH, Ware LB, Matthay MA. Negative-pressure pulmonary edema. Chest. 2016;150(4):927-933.
    1. Thiagarajan RR, Laussen PC. Negative pressure pulmonary edema in children-pathogenesis and clinical management. Pediatric Anesthesia. 2007;17(4):307-310.
    1. Kanter RK. Pulmonary edema associated with upper airway obstruction. Arch Pediatr Adolesc Med. 1984;138(4):356-358.

Grants and funding

LinkOut - more resources