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. 1986 Nov;175(3):189-93.
doi: 10.1016/0165-7992(86)90120-x.

Effects of human interferon-alpha on UV-induced DNA-repair synthesis and cell killing

N Suzuki

Effects of human interferon-alpha on UV-induced DNA-repair synthesis and cell killing

N Suzuki. Mutat Res. 1986 Nov.

Abstract

Cells of a human transformed cell line, RSb, which have unusually high sensitivity to UV killing and low DNA-repair capacity and which can be induced into antiviral states by human interferon (HuIFN)-alpha (Suzuki et al., 1982), acquired increased levels of DNA-repair synthesis and cell survival when pretreated with HuIFN-alpha before UV irradiation. The increased effects of HuIFN-alpha were also observed in other transformed VA13 cells and AK fibroblast cells.

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