Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Nov 21;44(44):4719-4721.
doi: 10.1093/eurheartj/ehad620.

Surgical pericardiotomy to treat heart failure with preserved ejection fraction: a first clinical study

Affiliations

Surgical pericardiotomy to treat heart failure with preserved ejection fraction: a first clinical study

Barry A Borlaug et al. Eur Heart J. .
No abstract available

Keywords: Cardiac surgery; Diastolic function; Haemodynamics; Heart failure; Heart failure with preserved ejection fraction; Pericardium.

PubMed Disclaimer

Figures

Figure 1
Figure 1
(A) Pulmonary wedge pressures prior to and following induction with general anaesthesia, following volume load manoeuver, then again at rest and repeat volume load following pericardiotomy. (B) The primary efficacy endpoint of change in pulmonary wedge pressure with volume loading was significantly reduced by pericardiotomy. (C, D) Changes in Kansas City Cardiomyopathy Questionnaire overall summary score (KCCQ-OSS) and peak oxygen consumption (VO2) during upright cycle ergometry stress testing. Each coloured dot represents an individual patient at given time point

Similar articles

Cited by

References

    1. Borlaug BA, Sharma K, Shah SJ, Ho JE. Heart failure with preserved ejection fraction: JACC scientific statement. J Am Coll Cardiol 2023;81:1810–34. 10.1016/j.jacc.2023.01.049 - DOI - PubMed
    1. Parasuraman SK, Loudon BL, Lowery C, Cameron D, Singh S, Schwarz K, et al. Diastolic ventricular interaction in heart failure with preserved ejection fraction. J Am Heart Assoc 2019;8:e010114. 10.1161/JAHA.118.010114 - DOI - PMC - PubMed
    1. Borlaug BA, Reddy YNV. The role of the pericardium in heart failure: implications for pathophysiology and treatment. JACC Heart Fail 2019;7:574–85. 10.1016/j.jchf.2019.03.021 - DOI - PMC - PubMed
    1. Reddy YNV, Olson TP, Obokata M, Melenovsky V, Borlaug BA. Hemodynamic correlates and diagnostic role of cardiopulmonary exercise testing in heart failure with preserved ejection fraction. JACC Heart Fail 2018;6:665–75. 10.1016/j.jchf.2018.03.003 - DOI - PMC - PubMed
    1. Obokata M, Olson TP, Reddy YNV, Melenovsky V, Kane GC, Borlaug BA. Haemodynamics, dyspnoea, and pulmonary reserve in heart failure with preserved ejection fraction. Eur Heart J 2018;39:2810–21. 10.1093/eurheartj/ehy268 - DOI - PMC - PubMed