Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Sep 24;21(2):e14391.
doi: 10.1111/iwj.14391. Online ahead of print.

Effects of refined nursing interventions in the operating room on surgical-site wound infection in patients with lung cancer: A meta-analysis

Xiaorui Wang  1 , Xia Li  1 , Jiying Zhang  1
Affiliations

Effects of refined nursing interventions in the operating room on surgical-site wound infection in patients with lung cancer: A meta-analysis

Xiaorui Wang et al. Int Wound J. .

Retraction in

Abstract

In this study, a meta-analysis was conducted to assess the effect of refined nursing interventions in the operating room on the incidence of surgical-site wound infections in patients undergoing lung cancer surgery to provide an evidence base for the prevention and management of nosocomial infections. A computerised literature search was used to identify randomised controlled trials (RCTs) on the application of refined nursing interventions in the operating room in patients undergoing lung cancer surgery published in the PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure (CNKI), VIP and Wanfang databases from their inception until July 2023. The literature screening, data extraction and quality assessment of the included studies were performed independently by two researchers. RevMan 5.4 software was used for the meta-analysis. Twenty-eight studies were included in the analysis, with a total of 2406 patients, including 1210 patients in the refined nursing intervention group and 1196 patients in the control group. The results of the meta-analysis showed that the refined nursing interventions in the operating room significantly reduced the incidence of surgical-site wound infections in patients undergoing lung cancer surgery, compared with the control group (1.82% vs. 6.52%, odds ratio: 0.30, 95% CI: 0.19-0.47, p < 0.001), and shortened the length of hospital stay (standardised mean difference: -1.51 days, 95% CI: -1.92 to -1.11 days, p < 0.001). Current evidence suggests that the application of refined nursing interventions in the operating room is effective at reducing the incidence of surgical-site wound infections and shortening the length of hospital stay in patients undergoing lung cancer surgery. However, owing to the small number and low quality of the studies, more high-quality RCTs with large sample sizes are needed to confirm these results.

Keywords: lung cancer; meta-analysis; operating room nursing; refined nursing; wound infection.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Study flow diagram.
FIGURE 2
FIGURE 2
The risk of bias graph of randomised controlled trials (RCTs).
FIGURE 3
FIGURE 3
The forest plots of surgical‐site wound infection.
FIGURE 4
FIGURE 4
The forest plots of patients' hospital stay.
FIGURE 5
FIGURE 5
Funnel plot analysis of wound infection.
See this image and copyright information in PMC

References

    1. Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209‐249. - PubMed
    1. Ye Y, Li L, Dai Q, Liu Y, Shen L. Comprehensive analysis of histone methylation modification regulators for predicting prognosis and drug sensitivity in lung adenocarcinoma. Front Cell Dev Biol. 2022;10:991980. - PMC - PubMed
    1. Kryczka J, Kryczka J, Czarnecka‐Chrebelska KH, Brzeziańska‐Lasota E. Molecular mechanisms of chemoresistance induced by cisplatin in NSCLC cancer therapy. Int J Mol Sci. 2021;22(16):8885. - PMC - PubMed
    1. Zhou Z, Wang Y, Niu Y, et al. How we assess the perioperative anxiety of surgical patients with pulmonary nodules: the revision of state‐trait anxiety inventory. J Cardiothorac Surg. 2020;15(1):324. - PMC - PubMed
    1. Guo XK, Gao HJ, Wang ML, et al. [Comparison of short‐term and long‐term outcomes between thoracoscopic pneumonectomy and open pneumonectomy for non‐small cell lung cancer: a study based on propensity score matching]. Zhonghua Wai Ke Za Zhi. 2020;58(2):131‐136. - PubMed

Publication types