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Review
. 2023 Sep 21:10:20499361231199582.
doi: 10.1177/20499361231199582. eCollection 2023 Jan-Dec.

Exploring the advancements of Australian OPAT

Affiliations
Review

Exploring the advancements of Australian OPAT

Tony Lai et al. Ther Adv Infect Dis. .

Abstract

Outpatient parenteral antimicrobial therapy (OPAT) in Australia has evolved from modest beginnings to a well-established health service with proven benefits in patient outcomes. This is a comprehensive review of the current state of art Australian OPAT with vignettes of the types of OPAT models of care, antimicrobial prescribing and antimicrobial use. In addition, we highlight the similarities and differences between OPAT to other countries and describe Australian OPAT experiences with COVID-19 and paediatrics. Australian OPAT continues to advance with OPAT antifungals, novel treatment options and upcoming high-impact research.

Keywords: antibiotics; antimicrobial stewardship; antimicrobials; outpatient parenteral antimicrobial therapy; outpatients.

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Conflict of interest statement

The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Hospitals contributing OPAT data to NAUSP. NAUSP, National Antimicrobial Utilisation Surveillance Program; OPAT, outpatient parenteral antimicrobial therapy.

References

    1. Williams DN, Baker CA, Kind AC, et al.. The history and evolution of outpatient parenteral antibiotic therapy (OPAT). Int J Antimicrob Agents 2015; 46: 307–312. - PubMed
    1. Esposito S, Noviello S, Leone S, et al.. Outpatient parenteral antibiotic therapy (OPAT) in different countries: a comparison. Int J Antimicrob Agents 2004; 24: 473–478. - PubMed
    1. Howden BP, Grayson ML. 5: Hospital-in-the-home treatment of infectious diseases. Med J Aust 2002; 176: 440–445. - PubMed
    1. Economic analysis of Hospital in the Home (HITH) Hospital in the Home Society of Australasia, Deloitte Access Economics, 2011.
    1. Leder K, Turnidge JD, Grayson ML. Home-based treatment of cellulitis with twice-daily cefazolin. Med J Aust 1998; 169: 519–522. - PubMed

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