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Case Reports
. 2023 Sep 21;15(9):e45692.
doi: 10.7759/cureus.45692. eCollection 2023 Sep.

Goserelin-Induced Chemical Burn: A Case Report and Review of the Literature

Aditya Mahadevan  1 , Brian Warnecke  2 , Elaine Chiao  1 , Nellie Nafissi  2 , Kritisha Parajuli  3 , Nejina Rijal  4 , Ritesh Parajuli  2
Affiliations
Case Reports

Goserelin-Induced Chemical Burn: A Case Report and Review of the Literature

Aditya Mahadevan et al. Cureus. .

Abstract

A chemical burn resulting from luteinizing hormone-releasing hormone agonists (LHRHa) is a rare adverse effect that has not been well-documented in prior literature. In this case report, we report a partial-thickness burn that developed following a single subcutaneous injection of goserelin. To our knowledge, this is the first description of goserelin-induced chemical burn in the literature. The importance of early identification and treatment of LHRHa-associated cutaneous reactions must be highlighted to ensure optimal oncologic management and patient comfort.

Keywords: aromatase inhibitor; chemical burn; goserelin; ovarian suppression; rash.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. 9x10 cm region of erythema and induration on the right lower abdominal wall
Figure 2
Figure 2. 9x10 cm area of erythema with small overlying fluid-filled vesicle
See this image and copyright information in PMC

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