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. 2023 Aug;59(4):505-521.
doi: 10.23736/S1973-9087.23.08086-3.

The impact of pregnancy on women with adolescent idiopathic scoliosis: a scoping review

Jean Theroux  1 , Benjamin T Brown  2   3 , Rosemary Marchese  3 , Michael Selby  4 , Vicki Cope  5   6 , Jeb McAviney  3 , Amber Beynon  2   7
Affiliations

The impact of pregnancy on women with adolescent idiopathic scoliosis: a scoping review

Jean Theroux et al. Eur J Phys Rehabil Med. 2023 Aug.

Abstract

Introduction: Adolescent idiopathic scoliosis is the most common spinal deformity encountered in adolescents and larger curves are more prevalent in girls. For females with scoliosis, women's health issues are of particular concern, especially pregnancy. The aim of this review was to summarise the best available evidence to determine the influence of pregnancy on scoliosis-related outcomes in women with scoliosis and whether scoliosis affects maternal-health outcomes, differentiating between patients who have been managed conservatively and/or surgically.

Evidence acquisition: A search was conducted using CINAHL, Scopus, Cochrane Database, MEDLINE, and EMBASE from inception to May 2023 to identify relevant articles in any language. The scoping review followed the PRISMA-ScR guidelines. Studies were eligible if they included pregnant women (primiparous or multiparous) with a diagnosis of scoliosis of unknown aetiology. The results were summarized by outcomes, including pregnancy and scoliosis-related outcomes and type of management.

Evidence synthesis: Our comprehensive search strategy identified 6872 articles, of which 50 articles were eligible for this review. Back pain appears to be more prevalent in this population during pregnancy and associated with the major curve and the decrease of lumbar lordosis. There have been reports of failed attempted spinal anaesthesia among patients with instrumented scoliosis correction and minor complications related to epidural anaesthesia at a higher rate compared to non-instrumented patients and healthy controls, however successful spinal analgesia can be achieved in patients with instrumented scoliosis correction. Overall, the caesarean section rate was similar in scoliosis patients compared to controls without scoliosis and to national averages. Curve progression occurs in some but not all patients during pregnancy, and this phenomenon occurs irrespective of the treatment received.

Conclusions: Higher-quality prospective longitudinal research is needed to understand the relationship between pregnancy and adolescent idiopathic scoliosis. Further, the patient's perspective, concerns and fears surrounding pregnancy with scoliosis are yet to be explored. Exploring the impact of pregnancy on women with adolescent idiopathic scoliosis would have clinically relevant outcomes and could help provide pertinent answers to patients and healthcare workers and help guide future research.

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Conflict of interest statement

Conflicts of interest: The authors certify that there is no conflict of interest with any financial organization regarding the material discussed in the manuscript.

Figures

Figure 1
Figure 1
—PRISMA flow diagram.
See this image and copyright information in PMC

References

    1. Weinstein SL, Dolan LA, Cheng JC, Danielsson A, Morcuende JA. Adolescent idiopathic scoliosis. Lancet 2008;371:1527–37. https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&l... 10.1016/S0140-6736(08)60658-3 - DOI - PubMed
    1. Konieczny MR, Senyurt H, Krauspe R. Epidemiology of adolescent idiopathic scoliosis. J Child Orthop 2013;7:3–9. https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&l... 10.1007/s11832-012-0457-4 - DOI - PMC - PubMed
    1. Cheng JC, Castelein RM, Chu WC, Danielsson AJ, Dobbs MB, Grivas TB, et al. Adolescent idiopathic scoliosis. Nat Rev Dis Primers 2015;1:15030. https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&l... 10.1038/nrdp.2015.30 - DOI - PubMed
    1. Weinstein SL. The Natural History of Adolescent Idiopathic Scoliosis. J Pediatr Orthop 2019;39(Supplement 1 Suppl 1):S44–6. https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&l... 10.1097/BPO.0000000000001350 - DOI - PubMed
    1. Jazini E, Raman T, Bressner J, Kebaish KM, Sponseller PD. Adolescent idiopathic scoliosis: considerations for the transition to adulthood. Semin Spine Surg 2015;27:62–9. 10.1053/j.semss.2015.01.013 - DOI

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