Published Erratum
doi: 10.1038/s41588-023-01531-7.
Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk
Nick Shrine #
1
, Abril G Izquierdo #
2
, Jing Chen #
2
, Richard Packer #
2
, Robert J Hall
3
, Anna L Guyatt
2
, Chiara Batini
2
4
, Rebecca J Thompson
3
, Chandan Pavuluri
5
, Vidhi Malik
5
, Brian D Hobbs
5
6
, Matthew Moll
5
, Wonji Kim
5
, Ruth Tal-Singer
7
, Per Bakke
8
, Katherine A Fawcett
2
, Catherine John
2
4
, Kayesha Coley
2
, Noemi Nicole Piga
2
, Alfred Pozarickij
9
, Kuang Lin
9
, Iona Y Millwood
9
10
, Zhengming Chen
9
10
, Liming Li
11
; China Kadoorie Biobank Collaborative Group; Sara R A Wijnant
12
13
14
, Lies Lahousse
13
14
, Guy Brusselle
12
14
, Andre G Uitterlinden
15
, Ani Manichaikul
16
, Elizabeth C Oelsner
17
, Stephen S Rich
16
, R Graham Barr
17
, Shona M Kerr
18
, Veronique Vitart
18
, Michael R Brown
19
, Matthias Wielscher
20
, Medea Imboden
21
22
, Ayoung Jeong
21
22
, Traci M Bartz
23
, Sina A Gharib
24
, Claudia Flexeder
25
26
27
, Stefan Karrasch
25
26
27
, Christian Gieger
27
28
, Annette Peters
27
29
, Beate Stubbe
30
, Xiaowei Hu
16
, Victor E Ortega
31
, Deborah A Meyers
32
, Eugene R Bleecker
32
, Stacey B Gabriel
33
, Namrata Gupta
33
, Albert Vernon Smith
34
35
, Jian'an Luan
36
, Jing-Hua Zhao
37
, Ailin F Hansen
38
, Arnulf Langhammer
39
40
, Cristen Willer
41
42
43
, Laxmi Bhatta
38
, David Porteous
44
, Blair H Smith
45
, Archie Campbell
44
, Tamar Sofer
46
47
48
, Jiwon Lee
46
, Martha L Daviglus
49
, Bing Yu
50
, Elise Lim
51
, Hanfei Xu
51
, George T O'Connor
52
, Gaurav Thareja
53
, Omar M E Albagha
54
55
; Qatar Genome Program Research (QGPR) Consortium; Karsten Suhre
53
56
, Raquel Granell
57
, Tariq O Faquih
58
, Pieter S Hiemstra
59
, Annelies M Slats
59
, Benjamin H Mullin
60
61
, Jennie Hui
62
63
64
, Alan James
62
, John Beilby
61
62
, Karina Patasova
65
66
, Pirro Hysi
65
67
, Jukka T Koskela
68
, Annah B Wyss
69
, Jianping Jin
70
, Sinjini Sikdar
69
71
, Mikyeong Lee
69
, Sebastian May-Wilson
72
, Nicola Pirastu
72
, Katherine A Kentistou
72
73
, Peter K Joshi
72
, Paul R H J Timmers
72
, Alexander T Williams
2
, Robert C Free
4
74
, Xueyang Wang
4
74
, John L Morrison
75
, Frank D Gilliland
75
, Zhanghua Chen
75
, Carol A Wang
76
77
, Rachel E Foong
78
79
, Sarah E Harris
80
, Adele Taylor
80
, Paul Redmond
80
, James P Cook
81
, Anubha Mahajan
82
83
, Lars Lind
84
, Teemu Palviainen
85
, Terho Lehtimäki
86
, Olli T Raitakari
87
88
, Jaakko Kaprio
85
, Taina Rantanen
89
, Kirsi H Pietiläinen
90
91
, Simon R Cox
80
, Craig E Pennell
76
77
92
, Graham L Hall
78
79
, W James Gauderman
75
, Chris Brightling
4
93
, James F Wilson
72
94
, Tuula Vasankari
95
96
, Tarja Laitinen
97
, Veikko Salomaa
98
, Dennis O Mook-Kanamori
58
99
, Nicholas J Timpson
57
100
, Eleftheria Zeggini
101
102
103
, Josée Dupuis
104
, Caroline Hayward
18
, Ben Brumpton
39
105
, Claudia Langenberg
36
106
107
, Stefan Weiss
108
, Georg Homuth
108
, Carsten Oliver Schmidt
109
, Nicole Probst-Hensch
21
22
, Marjo-Riitta Jarvelin
20
110
111
112
, Alanna C Morrison
19
, Ozren Polasek
113
, Igor Rudan
114
, Joo-Hyeon Lee
115
116
, Ian Sayers
3
, Emma L Rawlins
117
, Frank Dudbridge
2
, Edwin K Silverman
5
, David P Strachan
118
, Robin G Walters
9
10
, Andrew P Morris
119
, Stephanie J London
69
, Michael H Cho
5
, Louise V Wain
2
4
, Ian P Hall #
3
, Martin D Tobin #
120
121
Collaborators,
Affiliations
Collaborators
-
Said I Ismail, Wadha Al-Muftah, Radja Badji, Hamdi Mbarek, Dima Darwish, Tasnim Fadl, Heba Yasin, Maryem Ennaifar, Rania Abdellatif, Fatima Alkuwari, Muhammad Alvi, Yasser Al-Sarraj, Chadi Saad, Asmaa Althani, Eleni Fethnou, Fatima Qafoud, Eiman Alkhayat, Nahla Afifi, Sara Tomei, Wei Liu, Stephan Lorenz, Najeeb Syed, Hakeem Almabrazi, Fazulur Rehaman Vempalli, Ramzi Temanni, Tariq Abu Saqri, Mohammedhusen Khatib, Mehshad Hamza, Tariq Abu Zaid, Ahmed El Khouly, Tushar Pathare, Shafeeq Poolat, Rashid Al-Ali, Souhaila Al-Khodor, Mashael Alshafai, Ramin Badii, Lotfi Chouchane, Xavier Estivill, Khalid Fakhro, Younes Mokrab, Jithesh V Puthen, Zohreh Tatari
Affiliations
- 1 Department of Population Health Sciences, University of Leicester, Leicester, UK. nick.shrine@leicester.ac.uk.
- 2 Department of Population Health Sciences, University of Leicester, Leicester, UK.
- 3 Division of Respiratory Medicine and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK.
- 4 Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
- 5 Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
- 6 Harvard Medical School, Boston, MA, USA.
- 7 COPD Foundation, Washington DC, USA.
- 8 Department of Clinical Science, Unversity of Bergen, Bergen, Norway.
- 9 Nuffield Department of Population Health, University of Oxford, Oxford, UK.
- 10 MRC Population Health Research Unit, University of Oxford, Oxford, UK.
- 11 Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.
- 12 Department of Respiratory Diseases, Ghent Universital Hospital, Ghent, Belgium.
- 13 Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
- 14 Department of Epidemiology, Eramus Medical Center, Rotterdam, The Netherlands.
- 15 Department of Internal Medicine, Eramus Medical Center, Rotterdam, The Netherlands.
- 16 Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.
- 17 Department of Medicine, Columbia University Medical Center, New York, NY, USA.
- 18 Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
- 19 Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
- 20 MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
- 21 Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
- 22 Department of Public Health, University of Basel, Basel, Switzerland.
- 23 Cardiovascular Health Research Unit, Departments of Medicine and Biostatistics, University of Washington, Seattle, WA, USA.
- 24 Computational Medicine Core, Center for Lung Biology, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.
- 25 Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.
- 26 Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), Munich, Germany.
- 27 Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
- 28 Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
- 29 Institute for Medical Information Processing, Biometry and Epidemiology, Medical Faculty, Ludwig Maximilian University, Munich, Germany.
- 30 Department of Internal Medicine B-Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany.
- 31 Division of Respiratory Medicine, Department of Internal Medicine, Center for Individualized Medicine, Mayo Clinic, Scottsdale, AZ, USA.
- 32 Department of Medicine, University of Arizona, Tucson, AZ, USA.
- 33 Broad Institute of MIT and Harvard, Cambridge, MA, USA.
- 34 Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
- 35 Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
- 36 MRC Epidemiology Unit, Institute of Metabolic Science, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
- 37 Department of Public and Primary Care, Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.
- 38 K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Trondheim, Norway.
- 39 HUNT Research Centre, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Levanger, Norway.
- 40 Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway.
- 41 Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
- 42 Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
- 43 Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
- 44 Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
- 45 Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.
- 46 Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.
- 47 Department of Medicine, Harvard Medical School, Boston, MA, USA.
- 48 Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
- 49 Institute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA.
- 50 Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
- 51 Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA.
- 52 Pulmonary Center, School of Medicine, Boston University, Boston, MA, USA.
- 53 Bioinformatics Core, Weill Cornell Medicine-Qatar, Education City, Doha, Qatar.
- 54 College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.
- 55 Center for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
- 56 Department of Biophysics and Physiology, Weill Cornell Medicine, New York, NY, USA.
- 57 MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
- 58 Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
- 59 Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands.
- 60 Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.
- 61 School of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia.
- 62 Busselton Population Medical Research Institute, QEII Medical Centre, Nedlands, Western Australia, Australia.
- 63 School of Population and Global Health, University of Western Australia, Crawley, Western Australia, Australia.
- 64 PathWest Laboratory Medicine of WA, Nedlands, Western Australia, Australia.
- 65 Department of Twin Research and Genetic Epidemiology, King's College London School of Medicine, London, UK.
- 66 Division of Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
- 67 UCL Institute of Ophthalmology, University College London, London, UK.
- 68 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
- 69 Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA.
- 70 Westat, Durham, NC, USA.
- 71 Department of Mathematics and Statistics, Old Dominion University, Norfolk, VA, USA.
- 72 Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
- 73 Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
- 74 Department of Respiratory Sciences, University of Leicester, Leicester, UK.
- 75 Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
- 76 School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia.
- 77 Hunter Medical Research Institute, Newcastle, New South Wales, Australia.
- 78 Wal-yan Respiratory Research Centre, Telethon Kids Institute, Perth, Western Australia, Australia.
- 79 School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia.
- 80 Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK.
- 81 Department of Health Data Science, University of Liverpool, Liverpool, UK.
- 82 Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
- 83 Genentech, South San Francisco, CA, USA.
- 84 Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
- 85 Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland.
- 86 Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
- 87 Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
- 88 Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
- 89 Faculty of Sport and Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.
- 90 Obesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
- 91 Obesity and Abdominal Centers, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
- 92 Department of Maternity and Gynaecology, John Hunter Hospital, Newcastle, New South Wales, Australia.
- 93 Department of Infection, Inflammation and Immunity, Institute for Lung Health, University of Leicester, Leicester, UK.
- 94 MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK.
- 95 FILHA-Finnish Lung Health Association, Helsinki, Finland.
- 96 Department of Respiratory Diseases and Allergology, University of Turku, Turku, Finland.
- 97 Administration Center, Tampere University Hospital and University of Tampere, Tampere, Finland.
- 98 Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.
- 99 Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.
- 100 ALSPAC, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
- 101 Wellcome Sanger Institute, Cambridge, UK.
- 102 Institute of Translational Genomics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
- 103 Technical University of Munich (TUM) and Klinikum Rechts der Isar, TUM School of Medicine, Munich, Germany.
- 104 Department of Epidemiology, Biostatistics, and Occupational Health, School of Population and Global Health, McGill University, Montreal, Quebec, Canada.
- 105 Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
- 106 Precision Healthcare University Research Institute, Queen Mary University of London, London, UK.
- 107 Computational Medicine, Berlin Institute of Health at Charité, Universitätsmedizin Berlin, Berlin, Germany.
- 108 Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
- 109 Institute for Community Medicine, SHIP-Clinical Epidemiological Research, University Medicine Greifswald, Greifswald, Germany.
- 110 Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.
- 111 Biocenter Oulu, University of Oulu, Oulu, Finland.
- 112 Unit of Primary Health Care, Oulu University Hospital, OYS, Oulu, Finland.
- 113 School of Medicine, University of Split, Split, Croatia.
- 114 Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
- 115 Jeffrey Cheah Biomedical Centre, Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
- 116 Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
- 117 Wellcome Trust-CRUK Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
- 118 Population Health Research Institute, St George's University of London, London, UK.
- 119 Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.
- 120 Department of Population Health Sciences, University of Leicester, Leicester, UK. martin.tobin@leicester.ac.uk.
- 121 Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK. martin.tobin@leicester.ac.uk.
# Contributed equally.
- PMID: 37749248
- PMCID: PMC10562210
- DOI: 10.1038/s41588-023-01531-7
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Published Erratum
Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk
Nick Shrine et al.
Nat Genet.
2023 Oct.
Display options
Format
doi: 10.1038/s41588-023-01531-7.
Authors
Nick Shrine #
1
, Abril G Izquierdo #
2
, Jing Chen #
2
, Richard Packer #
2
, Robert J Hall
3
, Anna L Guyatt
2
, Chiara Batini
2
4
, Rebecca J Thompson
3
, Chandan Pavuluri
5
, Vidhi Malik
5
, Brian D Hobbs
5
6
, Matthew Moll
5
, Wonji Kim
5
, Ruth Tal-Singer
7
, Per Bakke
8
, Katherine A Fawcett
2
, Catherine John
2
4
, Kayesha Coley
2
, Noemi Nicole Piga
2
, Alfred Pozarickij
9
, Kuang Lin
9
, Iona Y Millwood
9
10
, Zhengming Chen
9
10
, Liming Li
11
; China Kadoorie Biobank Collaborative Group; Sara R A Wijnant
12
13
14
, Lies Lahousse
13
14
, Guy Brusselle
12
14
, Andre G Uitterlinden
15
, Ani Manichaikul
16
, Elizabeth C Oelsner
17
, Stephen S Rich
16
, R Graham Barr
17
, Shona M Kerr
18
, Veronique Vitart
18
, Michael R Brown
19
, Matthias Wielscher
20
, Medea Imboden
21
22
, Ayoung Jeong
21
22
, Traci M Bartz
23
, Sina A Gharib
24
, Claudia Flexeder
25
26
27
, Stefan Karrasch
25
26
27
, Christian Gieger
27
28
, Annette Peters
27
29
, Beate Stubbe
30
, Xiaowei Hu
16
, Victor E Ortega
31
, Deborah A Meyers
32
, Eugene R Bleecker
32
, Stacey B Gabriel
33
, Namrata Gupta
33
, Albert Vernon Smith
34
35
, Jian'an Luan
36
, Jing-Hua Zhao
37
, Ailin F Hansen
38
, Arnulf Langhammer
39
40
, Cristen Willer
41
42
43
, Laxmi Bhatta
38
, David Porteous
44
, Blair H Smith
45
, Archie Campbell
44
, Tamar Sofer
46
47
48
, Jiwon Lee
46
, Martha L Daviglus
49
, Bing Yu
50
, Elise Lim
51
, Hanfei Xu
51
, George T O'Connor
52
, Gaurav Thareja
53
, Omar M E Albagha
54
55
; Qatar Genome Program Research (QGPR) Consortium; Karsten Suhre
53
56
, Raquel Granell
57
, Tariq O Faquih
58
, Pieter S Hiemstra
59
, Annelies M Slats
59
, Benjamin H Mullin
60
61
, Jennie Hui
62
63
64
, Alan James
62
, John Beilby
61
62
, Karina Patasova
65
66
, Pirro Hysi
65
67
, Jukka T Koskela
68
, Annah B Wyss
69
, Jianping Jin
70
, Sinjini Sikdar
69
71
, Mikyeong Lee
69
, Sebastian May-Wilson
72
, Nicola Pirastu
72
, Katherine A Kentistou
72
73
, Peter K Joshi
72
, Paul R H J Timmers
72
, Alexander T Williams
2
, Robert C Free
4
74
, Xueyang Wang
4
74
, John L Morrison
75
, Frank D Gilliland
75
, Zhanghua Chen
75
, Carol A Wang
76
77
, Rachel E Foong
78
79
, Sarah E Harris
80
, Adele Taylor
80
, Paul Redmond
80
, James P Cook
81
, Anubha Mahajan
82
83
, Lars Lind
84
, Teemu Palviainen
85
, Terho Lehtimäki
86
, Olli T Raitakari
87
88
, Jaakko Kaprio
85
, Taina Rantanen
89
, Kirsi H Pietiläinen
90
91
, Simon R Cox
80
, Craig E Pennell
76
77
92
, Graham L Hall
78
79
, W James Gauderman
75
, Chris Brightling
4
93
, James F Wilson
72
94
, Tuula Vasankari
95
96
, Tarja Laitinen
97
, Veikko Salomaa
98
, Dennis O Mook-Kanamori
58
99
, Nicholas J Timpson
57
100
, Eleftheria Zeggini
101
102
103
, Josée Dupuis
104
, Caroline Hayward
18
, Ben Brumpton
39
105
, Claudia Langenberg
36
106
107
, Stefan Weiss
108
, Georg Homuth
108
, Carsten Oliver Schmidt
109
, Nicole Probst-Hensch
21
22
, Marjo-Riitta Jarvelin
20
110
111
112
, Alanna C Morrison
19
, Ozren Polasek
113
, Igor Rudan
114
, Joo-Hyeon Lee
115
116
, Ian Sayers
3
, Emma L Rawlins
117
, Frank Dudbridge
2
, Edwin K Silverman
5
, David P Strachan
118
, Robin G Walters
9
10
, Andrew P Morris
119
, Stephanie J London
69
, Michael H Cho
5
, Louise V Wain
2
4
, Ian P Hall #
3
, Martin D Tobin #
120
121
Collaborators
-
Said I Ismail, Wadha Al-Muftah, Radja Badji, Hamdi Mbarek, Dima Darwish, Tasnim Fadl, Heba Yasin, Maryem Ennaifar, Rania Abdellatif, Fatima Alkuwari, Muhammad Alvi, Yasser Al-Sarraj, Chadi Saad, Asmaa Althani, Eleni Fethnou, Fatima Qafoud, Eiman Alkhayat, Nahla Afifi, Sara Tomei, Wei Liu, Stephan Lorenz, Najeeb Syed, Hakeem Almabrazi, Fazulur Rehaman Vempalli, Ramzi Temanni, Tariq Abu Saqri, Mohammedhusen Khatib, Mehshad Hamza, Tariq Abu Zaid, Ahmed El Khouly, Tushar Pathare, Shafeeq Poolat, Rashid Al-Ali, Souhaila Al-Khodor, Mashael Alshafai, Ramin Badii, Lotfi Chouchane, Xavier Estivill, Khalid Fakhro, Younes Mokrab, Jithesh V Puthen, Zohreh Tatari
Affiliations
- 1 Department of Population Health Sciences, University of Leicester, Leicester, UK. nick.shrine@leicester.ac.uk.
- 2 Department of Population Health Sciences, University of Leicester, Leicester, UK.
- 3 Division of Respiratory Medicine and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK.
- 4 Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
- 5 Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
- 6 Harvard Medical School, Boston, MA, USA.
- 7 COPD Foundation, Washington DC, USA.
- 8 Department of Clinical Science, Unversity of Bergen, Bergen, Norway.
- 9 Nuffield Department of Population Health, University of Oxford, Oxford, UK.
- 10 MRC Population Health Research Unit, University of Oxford, Oxford, UK.
- 11 Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.
- 12 Department of Respiratory Diseases, Ghent Universital Hospital, Ghent, Belgium.
- 13 Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
- 14 Department of Epidemiology, Eramus Medical Center, Rotterdam, The Netherlands.
- 15 Department of Internal Medicine, Eramus Medical Center, Rotterdam, The Netherlands.
- 16 Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.
- 17 Department of Medicine, Columbia University Medical Center, New York, NY, USA.
- 18 Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
- 19 Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
- 20 MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
- 21 Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
- 22 Department of Public Health, University of Basel, Basel, Switzerland.
- 23 Cardiovascular Health Research Unit, Departments of Medicine and Biostatistics, University of Washington, Seattle, WA, USA.
- 24 Computational Medicine Core, Center for Lung Biology, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.
- 25 Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.
- 26 Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), Munich, Germany.
- 27 Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
- 28 Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
- 29 Institute for Medical Information Processing, Biometry and Epidemiology, Medical Faculty, Ludwig Maximilian University, Munich, Germany.
- 30 Department of Internal Medicine B-Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany.
- 31 Division of Respiratory Medicine, Department of Internal Medicine, Center for Individualized Medicine, Mayo Clinic, Scottsdale, AZ, USA.
- 32 Department of Medicine, University of Arizona, Tucson, AZ, USA.
- 33 Broad Institute of MIT and Harvard, Cambridge, MA, USA.
- 34 Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
- 35 Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
- 36 MRC Epidemiology Unit, Institute of Metabolic Science, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
- 37 Department of Public and Primary Care, Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.
- 38 K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Trondheim, Norway.
- 39 HUNT Research Centre, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Levanger, Norway.
- 40 Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway.
- 41 Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
- 42 Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
- 43 Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
- 44 Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
- 45 Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.
- 46 Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.
- 47 Department of Medicine, Harvard Medical School, Boston, MA, USA.
- 48 Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
- 49 Institute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA.
- 50 Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
- 51 Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA.
- 52 Pulmonary Center, School of Medicine, Boston University, Boston, MA, USA.
- 53 Bioinformatics Core, Weill Cornell Medicine-Qatar, Education City, Doha, Qatar.
- 54 College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.
- 55 Center for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
- 56 Department of Biophysics and Physiology, Weill Cornell Medicine, New York, NY, USA.
- 57 MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
- 58 Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
- 59 Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands.
- 60 Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.
- 61 School of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia.
- 62 Busselton Population Medical Research Institute, QEII Medical Centre, Nedlands, Western Australia, Australia.
- 63 School of Population and Global Health, University of Western Australia, Crawley, Western Australia, Australia.
- 64 PathWest Laboratory Medicine of WA, Nedlands, Western Australia, Australia.
- 65 Department of Twin Research and Genetic Epidemiology, King's College London School of Medicine, London, UK.
- 66 Division of Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
- 67 UCL Institute of Ophthalmology, University College London, London, UK.
- 68 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
- 69 Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA.
- 70 Westat, Durham, NC, USA.
- 71 Department of Mathematics and Statistics, Old Dominion University, Norfolk, VA, USA.
- 72 Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
- 73 Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
- 74 Department of Respiratory Sciences, University of Leicester, Leicester, UK.
- 75 Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
- 76 School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia.
- 77 Hunter Medical Research Institute, Newcastle, New South Wales, Australia.
- 78 Wal-yan Respiratory Research Centre, Telethon Kids Institute, Perth, Western Australia, Australia.
- 79 School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia.
- 80 Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK.
- 81 Department of Health Data Science, University of Liverpool, Liverpool, UK.
- 82 Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
- 83 Genentech, South San Francisco, CA, USA.
- 84 Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
- 85 Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland.
- 86 Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
- 87 Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
- 88 Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
- 89 Faculty of Sport and Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.
- 90 Obesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
- 91 Obesity and Abdominal Centers, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
- 92 Department of Maternity and Gynaecology, John Hunter Hospital, Newcastle, New South Wales, Australia.
- 93 Department of Infection, Inflammation and Immunity, Institute for Lung Health, University of Leicester, Leicester, UK.
- 94 MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK.
- 95 FILHA-Finnish Lung Health Association, Helsinki, Finland.
- 96 Department of Respiratory Diseases and Allergology, University of Turku, Turku, Finland.
- 97 Administration Center, Tampere University Hospital and University of Tampere, Tampere, Finland.
- 98 Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.
- 99 Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.
- 100 ALSPAC, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
- 101 Wellcome Sanger Institute, Cambridge, UK.
- 102 Institute of Translational Genomics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
- 103 Technical University of Munich (TUM) and Klinikum Rechts der Isar, TUM School of Medicine, Munich, Germany.
- 104 Department of Epidemiology, Biostatistics, and Occupational Health, School of Population and Global Health, McGill University, Montreal, Quebec, Canada.
- 105 Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
- 106 Precision Healthcare University Research Institute, Queen Mary University of London, London, UK.
- 107 Computational Medicine, Berlin Institute of Health at Charité, Universitätsmedizin Berlin, Berlin, Germany.
- 108 Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
- 109 Institute for Community Medicine, SHIP-Clinical Epidemiological Research, University Medicine Greifswald, Greifswald, Germany.
- 110 Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.
- 111 Biocenter Oulu, University of Oulu, Oulu, Finland.
- 112 Unit of Primary Health Care, Oulu University Hospital, OYS, Oulu, Finland.
- 113 School of Medicine, University of Split, Split, Croatia.
- 114 Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
- 115 Jeffrey Cheah Biomedical Centre, Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
- 116 Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
- 117 Wellcome Trust-CRUK Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
- 118 Population Health Research Institute, St George's University of London, London, UK.
- 119 Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.
- 120 Department of Population Health Sciences, University of Leicester, Leicester, UK. martin.tobin@leicester.ac.uk.
- 121 Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK. martin.tobin@leicester.ac.uk.
# Contributed equally.
- PMID: 37749248
- PMCID: PMC10562210
- DOI: 10.1038/s41588-023-01531-7
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Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.Shrine N, Izquierdo AG, Chen J, Packer R, Hall RJ, Guyatt AL, Batini C, Thompson RJ, Pavuluri C, Malik V, Hobbs BD, Moll M, Kim W, Tal-Singer R, Bakke P, Fawcett KA, John C, Coley K, Piga NN, Pozarickij A, Lin K, Millwood IY, Chen Z, Li L; China Kadoorie Biobank Collaborative Group; Wijnant SRA, Lahousse L, Brusselle G, Uitterlinden AG, Manichaikul A, Oelsner EC, Rich SS, Barr RG, Kerr SM, Vitart V, Brown MR, Wielscher M, Imboden M, Jeong A, Bartz TM, Gharib SA, Flexeder C, Karrasch S, Gieger C, Peters A, Stubbe B, Hu X, Ortega VE, Meyers DA, Bleecker ER, Gabriel SB, Gupta N, Smith AV, Luan J, Zhao JH, Hansen AF, Langhammer A, Willer C, Bhatta L, Porteous D, Smith BH, Campbell A, Sofer T, Lee J, Daviglus ML, Yu B, Lim E, Xu H, O'Connor GT, Thareja G, Albagha OME; Qatar Genome Program Research (QGPR) Consortium; Suhre K, Granell R, Faquih TO, Hiemstra PS, Slats AM, Mullin BH, Hui J, James A, Beilby J, Patasova K, Hysi P, Koskela JT, Wyss AB, Jin J, Sikdar S, Lee M, May-Wilson S, Pirastu N, Kentistou KA, Joshi PK, Timmers PRHJ, Williams AT, Free RC, Wang X, Morrison JL, Gilliland FD, Chen Z, Wang CA, Foong RE, Harris SE, Taylor A, Redmond P, Cook JP, Mahajan A, Lind L, Palviainen T,… See abstract for full author list ➔ Shrine N, et al. Nat Genet. 2023 Mar;55(3):410-422. doi: 10.1038/s41588-023-01314-0. Epub 2023 Mar 13. Nat Genet. 2023. PMID: 36914875 Free PMC article.
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