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Case Reports
. 2023 Nov 1;45(8):e1018-e1022.
doi: 10.1097/MPH.0000000000002756. Epub 2023 Sep 26.

Wilms Tumor in Child With Trisomy 18 and Horseshoe Kidney

Elizabeth Chen  1 , Lisa Hackney  2 , Kristen VanHeyst  2 , Eiichi A Miyasaka  3
Affiliations
Case Reports

Wilms Tumor in Child With Trisomy 18 and Horseshoe Kidney

Elizabeth Chen et al. J Pediatr Hematol Oncol. .

Abstract

Trisomy 18 is associated with several congenital malformations, including horseshoe kidney. It can be full, partial, or mosaic, and mosaicism is often associated with lesser severity and longer life expectancy, placing patients at greater risk of developing neoplasms or malignancies. One common tumor among children with Trisomy 18 is Wilms tumor, which is also associated with renal congenital abnormalities such as horseshoe kidney. We present a case describing the occurrence of these three characteristics: development of Wilms tumor in a patient with Trisomy 18 and a horseshoe kidney and discuss treatment with regards to these conditions.

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Conflict of interest statement

The authors declare no conflict of interest.

References

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    1. Schiappacasse G, Aguirre J, Soffia P, et al. CT findings of the main pathological conditions associated with horseshoe kidneys. Br J Radiol. 2015;88:20140456.

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