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. 2024 Jan;15(1):33-60.
doi: 10.1007/s13300-023-01465-7. Epub 2023 Sep 26.

New-Onset Diabetes Mellitus in COVID-19: A Scoping Review

Anca Pantea Stoian  1   2 , Ioana-Cristina Bica  3 , Teodor Salmen  2 , Wael Al Mahmeed  4 , Khalid Al-Rasadi  5 , Kamila Al-Alawi  6 , Maciej Banach  7   8   9 , Yajnavalka Banerjee  10 , Antonio Ceriello  11 , Mustafa Cesur  12 , Francesco Cosentino  13 , Alberto Firenze  14 , Massimo Galia  15 , Su-Yen Goh  16 , Andrej Janez  17 , Sanjay Kalra  18 , Nitin Kapoor  19   20 , Peter Kempler  21 , Nader Lessan  22 , Paulo Lotufo  23 , Dimitri P Mikhailidis  10   24 , Luigi Nibali  25 , Nikolaos Papanas  26 , Tiffany Powell-Wiley  27 , Ali A Rizvi  28 , Amirhossein Sahebkar  29   30   31 , Raul D Santos  32   33 , Peter P Toth  33   34 , Vijay Viswanathan  35 , Manfredi Rizzo  1   10   36 ; Cardiometabolic Panel of International Experts on Syndemic COVID-19 (CAPISCO)
Affiliations

New-Onset Diabetes Mellitus in COVID-19: A Scoping Review

Anca Pantea Stoian et al. Diabetes Ther. 2024 Jan.

Erratum in

  • Correction to: New-Onset Diabetes Mellitus in COVID-19: A Scoping Review.
    Pantea Stoian A, Bica IC, Salmen T, Al Mahmeed W, Al-Rasadi K, Al-Alawi K, Banach M, Banerjee Y, Ceriello A, Cesur M, Cosentino F, Firenze A, Galia M, Goh SY, Janez A, Kalra S, Kapoor N, Kempler P, Lessan N, Lotufo P, Mikhailidis DP, Nibali L, Papanas N, Powell-Wiley T, Rizvi AA, Sahebkar A, Santos RD, Toth PP, Viswanathan V, Rizzo M; Cardiometabolic Panel of International Experts on Syndemic COVID-19 (CAPISCO). Pantea Stoian A, et al. Diabetes Ther. 2024 Jan;15(1):297-299. doi: 10.1007/s13300-023-01494-2. Diabetes Ther. 2024. PMID: 37964156 Free PMC article. No abstract available.

Abstract

Introduction: The coronavirus disease 2019 (COVID-19) pandemic became superimposed on the pre-existing obesity and diabetes mellitus (DM) pandemics. Since COVID-19 infection alters the metabolic equilibrium, it may induce pathophysiologic mechanisms that potentiate new-onset DM, and we evaluated this issue.

Method: A systematic review of the literature published from the 1 January 2020 until the 20 July 2023 was performed (PROSPERO registration number CRD42022341638). We included only full-text articles of both human clinical and randomized controlled trials published in English and enrolling adults (age > 18 years old) with ongoing or preceding COVID-19 in whom hyperglycemia was detected. The search was based on the following criteria: "(new-onset diabetes mellitus OR new-onset DM) AND (COVID-19) AND adults".

Results: Articles on MEDLINE (n = 70) and the Web of Science database (n = 16) were included and analyzed by two researchers who selected 20 relevant articles. We found evidence of a bidirectional relationship between COVID-19 and DM.

Conclusions: This link operates as a pathophysiological mechanism supported by epidemiological data and also by the clinical and biological findings obtained from the affected individuals. The COVID-19 pandemic raised the incidence of DM through different pathophysiological and psychosocial factors.

Keywords: Coronavirus disease 2019; Diabetes mellitus; Hyperglycemia; New-onset diabetes; New-onset hyperglycemia; Newly diagnosed diabetes; Prediabetes; Severe acute respiratory syndrome coronavirus-2 infection.

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Conflict of interest statement

All named authors confirm that they have no conflicts of interest to disclose.

Figures

Fig. 1
Fig. 1
Flowchart of the study selection process according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) recommendations
Fig. 2
Fig. 2
Different mechanisms proposed as possible causes of hyperglycemia in SARS-CoV-2 infection
See this image and copyright information in PMC

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