Invasive Gastrointestinal Mucormycosis
- PMID: 37753101
- PMCID: PMC10519550
- DOI: 10.14309/crj.0000000000001161
Invasive Gastrointestinal Mucormycosis
Abstract
Invasive mucormycosis is an opportunistic fungal infection that can be devastating in immunosuppressed patients. Gastrointestinal infection is rare, but carries among the highest mortality rates of its major clinical presentations. We present a case of invasive gastrointestinal mucormycosis in a patient who underwent recent chemotherapy and autologous stem cell transplant. Initial histopathology revealed cytomegalovirus infection, which was treated before subsequent diagnosis of mucormycosis on repeat bowel biopsy. Our case highlights a myriad of risk factors that increase the potential for serious infection by this pervasive fungus.
Keywords: cytomegalovirus; disseminated; immunosuppressed; mucormycosis.
© 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.
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References
-
- Lee SC, Idmurm A. 8. Fingal sex: The mucoromycota. In: Heitman J, Howlett BJ, Crous PW, Stukenbrock EH, James TY, Gow NA. (eds). The Fungal Kingdom. Wiley: Hoboken, NJ, 2018, pp 177–92.
-
- Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP. Epidemiology and clinical manifestations of mucormycosis. Clin Infect Dis. 2012;54(Suppl 1):S23–34. - PubMed
-
- Roden MM, Zaoutis TE, Buchanan WL, et al. . Epidemiology and outcome of zygomycosis: A review of 929 reported cases. Clin Infect Dis. 2005;41(5):634–53. - PubMed
-
- Farmakiotis D, Kontoyiannis DP. Mucormycoses. Infect Dis Clin North Am. 2016;30(1):143–63. - PubMed
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