Adult Highlights From the Extracorporeal Life Support Organization Registry: 2017-2022

Aniket S Rali¹, Adeel Abbasi², Peta M A Alexander^{3

4}, Marc M Anders⁵, Deepa J Arachchillage⁶, Ryan P Barbaro⁷, Alexander D Fox⁸, Matthew L Friedman⁹, Maximilian V Malfertheiner¹⁰, Kollengode Ramanathan¹¹, Jordi Riera^{12

13}, Peter Rycus⁸, Peter Schellongowski¹⁴, Kiran Shekar^{15

16}, Joseph E Tonna¹⁷, Akram M Zaaqoq¹⁸; ELSO Scientific Oversight Committee

Affiliations

¹ From the Division of Cardiovascular Diseases, Vanderbilt University Medical Center, Nashville, Tennessee.
² Division of Pulmonary Critical Care and Sleep, Department of Medicine, Warren Alpert School of Medicine at Brown University, Providence, Rhode Island.
³ Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts.
⁴ Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.
⁵ Baylor College of Medicine and Texas Children's Hospital, Houston, Texas.
⁶ Center for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.
⁷ Division of Pediatric Critical Care Medicine and Child Health Evaluation and Research Center, University of Michigan, Ann Arbor, Michigan.
⁸ Extracorporeal Life Support Organization, Ann Arbor, Michigan.
⁹ Division of Pediatric Critical Care, Indiana School of Medicine, Indianapolis, Indiana.
¹⁰ Department of Internal Medicine, Cardiology and Pneumology, University Medical Center, Regensburg, Germany.
¹¹ Cardiothoracic Intensive Care Unit, National University Heart Center, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
¹² Department of Critical Care, Vall d'Hebron University Hospital, Barcelona, Spain.
¹³ SODIR, Vall d'Hebron Research Institute, Barcelona, Spain.
¹⁴ ICU 13i2, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
¹⁵ Adult Intensive Care Services, Prince Charles Hospital, Brisbane, Queensland, Australia.
¹⁶ Faculty of Medicine, The University of Queensland, Queensland, Australia.
¹⁷ Division of Cardiothoracic Surgery, University of Utah Health, Salt Lake City, Utah.
¹⁸ Division of Critical Care, Department of Anesthesiology, University of Virginia, Charlottesville, Virginia.

PMID: 37755405
DOI: 10.1097/MAT.0000000000002038

Review

Adult Highlights From the Extracorporeal Life Support Organization Registry: 2017-2022

Aniket S Rali et al. ASAIO J. 2024.

. 2024 Jan 1;70(1):1-7.

doi: 10.1097/MAT.0000000000002038. Epub 2023 Sep 26.

Authors

Affiliations

¹ From the Division of Cardiovascular Diseases, Vanderbilt University Medical Center, Nashville, Tennessee.
² Division of Pulmonary Critical Care and Sleep, Department of Medicine, Warren Alpert School of Medicine at Brown University, Providence, Rhode Island.
³ Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts.
⁴ Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.
⁵ Baylor College of Medicine and Texas Children's Hospital, Houston, Texas.
⁶ Center for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.
⁷ Division of Pediatric Critical Care Medicine and Child Health Evaluation and Research Center, University of Michigan, Ann Arbor, Michigan.
⁸ Extracorporeal Life Support Organization, Ann Arbor, Michigan.
⁹ Division of Pediatric Critical Care, Indiana School of Medicine, Indianapolis, Indiana.
¹⁰ Department of Internal Medicine, Cardiology and Pneumology, University Medical Center, Regensburg, Germany.
¹¹ Cardiothoracic Intensive Care Unit, National University Heart Center, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
¹² Department of Critical Care, Vall d'Hebron University Hospital, Barcelona, Spain.
¹³ SODIR, Vall d'Hebron Research Institute, Barcelona, Spain.
¹⁴ ICU 13i2, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
¹⁵ Adult Intensive Care Services, Prince Charles Hospital, Brisbane, Queensland, Australia.
¹⁶ Faculty of Medicine, The University of Queensland, Queensland, Australia.
¹⁷ Division of Cardiothoracic Surgery, University of Utah Health, Salt Lake City, Utah.
¹⁸ Division of Critical Care, Department of Anesthesiology, University of Virginia, Charlottesville, Virginia.

PMID: 37755405
DOI: 10.1097/MAT.0000000000002038

Abstract

The Extracorporeal Life Support Organization (ELSO) registry captures clinical data and outcomes on patients receiving extracorporeal membrane oxygenation (ECMO) support across the globe at participating centers. It provides a very unique opportunity to benchmark outcomes and analyze the clinical course to help identify ways of improving patient outcomes. In this review, we summarize select adult ECMO articles published using the ELSO registry over the past 5 years. These articles highlight innovative utilization of the registry data in generating hypotheses for future clinical trials. Members of the ELSO Scientific Oversight Committee can be found here: https://www.elso.org/registry/socmembers.aspx .

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Conflict of interest statement

Disclosure: P.S. received personal fees from Fresenius and Getinge and a scientific grant from the European Society of Intensive Care Medicine and the European Commission (Horizon 2020 Fast Track to Innovation: NCT04115709). K.S. acknowledges research support from Metro North Hospital and Health Service. A.A. receives research support from Francis Family Foundation and NIGMS P20 GM 103652 grant. The other authors have no conflicts of interest to report.

References

1. Thiagarajan RR, Barbaro RP, Rycus PT, et al.; ELSO Member Centers: Extracorporeal life support organization registry international report 2016. ASAIO J. 63: 60–67, 2017.
1. Rali AS, Chandler J, Sauer A, Solomon MA, Shah Z: Venoarterial extracorporeal membrane oxygenation in cardiogenic shock: Lifeline of modern day CICU. J Intensive Care Med. 36: 290–303, 2021.
1. Toomasian JM, Snedecor SM, Cornell RG, Cilley RE, Bartlett RH: National experience with extracorporeal membrane oxygenation for newborn respiratory failure. Data from 715 cases. ASAIO Trans. 34: 140–147, 1988.
1. Henry BM, Lippi G: Poor survival with extracorporeal membrane oxygenation in acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19): Pooled analysis of early reports. J Crit Care. 58: 27–28, 2020.
1. Barbaro RP, MacLaren G, Boonstra PS, et al.; Extracorporeal Life Support Organization: Extracorporeal membrane oxygenation support in COVID-19: An international cohort study of the Extracorporeal Life Support Organization Registry. Lancet. 396: 1071–1078, 2020.

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Adult Highlights From the Extracorporeal Life Support Organization Registry: 2017-2022

Affiliations

Adult Highlights From the Extracorporeal Life Support Organization Registry: 2017-2022

Authors

Affiliations

Abstract

Conflict of interest statement

References

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Miscellaneous