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Comment
. 2023 Nov;22(11):871.
doi: 10.1038/d41573-023-00155-0.

Rewired proteostasis in KRAS inhibitor resistance

Alex Eccleston
Comment

Rewired proteostasis in KRAS inhibitor resistance

Alex Eccleston. Nat Rev Drug Discov. 2023 Nov.
No abstract available

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Comment on

  • Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors.
    Lv X, Lu X, Cao J, Luo Q, Ding Y, Peng F, Pataer A, Lu D, Han D, Malmberg E, Chan DW, Wang X, Savage SR, Mao S, Yu J, Peng F, Yan L, Meng H, Maneix L, Han Y, Chen Y, Yao W, Chang EC, Catic A, Lin X, Miles G, Huang P, Sun Z, Burt B, Wang H, Wang J, Yao QC, Zhang B, Roth JA, O'Malley BW, Ellis MJ, Rimawi MF, Ying H, Chen X. Lv X, et al. Science. 2023 Sep 8;381(6662):eabn4180. doi: 10.1126/science.abn4180. Epub 2023 Sep 8. Science. 2023. PMID: 37676964 Free PMC article.

References

    1. Lv, X. et al. Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors. Science 381, eabn4180 (2023) - PubMed

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