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Review
. 2023 Sep 19;24(18):14298.
doi: 10.3390/ijms241814298.

Novel Material Optimization Strategies for Developing Upgraded Abdominal Meshes

Alfred Najm  1   2 , Adelina-Gabriela Niculescu  3   4 , Marius Rădulescu  5 , Bogdan Severus Gaspar  1   2 , Alexandru Mihai Grumezescu  3   4   6 , Mircea Beuran  1   2
Affiliations
Review

Novel Material Optimization Strategies for Developing Upgraded Abdominal Meshes

Alfred Najm et al. Int J Mol Sci. .

Abstract

Over 20 million hernias are operated on globally per year, with most interventions requiring mesh reinforcement. A wide range of such medical devices are currently available on the market, most fabricated from synthetic polymers. Yet, searching for an ideal mesh is an ongoing process, with continuous efforts directed toward developing upgraded implants by modifying existing products or creating innovative systems from scratch. In this regard, this review presents the most frequently employed polymers for mesh fabrication, outlining the market available products and their relevant characteristics, further focusing on the state-of-the-art mesh approaches. Specifically, we mainly discuss recent studies concerning coating application, nanomaterials addition, stem cell seeding, and 3D printing of custom mesh designs.

Keywords: abdominal meshes; composite materials; improved biomedical devices; mesh materials; optimization strategies; polymer materials.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Mesh classification according to material, pore size, and weight. Created based on information from [11].
Figure 2
Figure 2
Main directions in mesh optimization strategies.
See this image and copyright information in PMC

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