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Review
. 2023 Sep 13;11(9):2309.
doi: 10.3390/microorganisms11092309.

Emerging Tick-Borne Dabie bandavirus: Virology, Epidemiology, and Prevention

Eun-Ha Kim  1 , Su-Jin Park  2
Affiliations
Review

Emerging Tick-Borne Dabie bandavirus: Virology, Epidemiology, and Prevention

Eun-Ha Kim et al. Microorganisms. .

Abstract

Severe Fever with Thrombocytopenia Syndrome (SFTS), caused by Dabie bandavirus (SFTSV), is an emerging infectious disease first identified in China. Since its discovery, infections have spread throughout East Asian countries primarily through tick bites but also via transmission between animals and humans. The expanding range of ticks, the primary vectors for SFTSV, combined with migration patterns of tick-carrying birds, sets the stage for the global spread of this virus. SFTSV rapidly evolves due to continuous mutation and reassortment; currently, no approved vaccines or antiviral drugs are available. Thus, the threat this virus poses to global health is unmistakable. This review consolidates the most recent research on SFTSV, including its molecular characteristics, transmission pathways through ticks and other animals, as well as the progress in antiviral drug and vaccine development, encompassing animal models and clinical trials.

Keywords: Dabie bandavirus; public health; severe fever with thrombocytopenia syndrome.

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Conflict of interest statement

The authors declare no conflict of interest.

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