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. 2023 Sep 21;28(18):6747.
doi: 10.3390/molecules28186747.

Poly Caprolactam Supported Hexaethylene Glycolic Imidazolium Ionic Liquid as a Heterogeneous Promoter for Nucleophilic Fluorination

Mudumala Veeranarayana Reddy  1 , Keun Heok Park  1 , Dong Wook Kim  1
Affiliations

Poly Caprolactam Supported Hexaethylene Glycolic Imidazolium Ionic Liquid as a Heterogeneous Promoter for Nucleophilic Fluorination

Mudumala Veeranarayana Reddy et al. Molecules. .

Abstract

Hexaethylene glycolic vinyl imidazolium (hexaEGVIM) was supported on N-vinyl caprolactam via covalent bonds through simple copolymerization to form poly caprolactam-supported hexaethylene glycol-substituted imidazolium salts (PCLS-hexaEGIM). The resulting heterogeneous PCLS-hexaEGIM promoter was active, selective, and stable for aliphatic nucleophilic substitution reactions using alkali metal salts. The alkali metal salts dramatically enhanced the reactivity of this heterogeneous catalyst with easily isolable higher product yields, reducing the formation of by-products. Therefore, nucleophilic fluorination and other substitution reactions can act as highly efficient catalysts in various sulfonyloxyalkanes and haloalkanes with regard to their corresponding fluorinated products.

Keywords: heterogeneous promoter; ionin liquid; nucleophilic fluorination; polymer supported ionic liquid.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Polymer-supported imidazolium salts.
Scheme 1
Scheme 1
Preparation of PCLS-hexaEGIM.
Figure 2
Figure 2
(a–c) XPS pattern and (d) TGA patterns of PCLS-hexaEGIM.
See this image and copyright information in PMC

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