Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Sep 3;12(9):1127.
doi: 10.3390/pathogens12091127.

Mucosal Relapse of Visceral Leishmaniasis in a Child with SARS-CoV-2 Infection

Claudia Colomba  1   2 , Giovanni Boncori  1 , Chiara Albano  1 , Valeria Garbo  1 , Sara Bagarello  1 , Anna Condemi  1 , Salvatore Giordano  2 , Antonio Cascio  1   3
Affiliations

Mucosal Relapse of Visceral Leishmaniasis in a Child with SARS-CoV-2 Infection

Claudia Colomba et al. Pathogens. .

Abstract

Leishmaniasis is a vector-borne disease caused by protozoan parasites of the genus Leishmania and is transmitted through the bite of infected female sandflies. In the Mediterranean region, visceral leishmaniasis is caused by Leishmania. infantum, and it is usually responsible for symptoms such as fever, pancytopenia and enlargement of the liver and spleen. Relapse is rare in immunocompetent patients as much as the mucous involvement. We present a rare case of mucosal relapse of visceral leishmaniasis in a child with SARS-CoV-2 infection and perform an extensive review of the literature about leishmaniasis relapses in children. Atypical mucosal involvement during Leishmaniasis relapse is an eventuality in pediatric patients. Clinical follow-up and periodic PCR tests must be considered essential for the early recognition and treatment of an eventual relapse.

Keywords: leishmaniasis; mucosal; pediatric; relapse; visceral.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Literature review process.
See this image and copyright information in PMC

References

    1. Pessoa F.S., Salgado I.A., Gonçalves V.C., Martins A.C., Pessoa L.S., Junior L.B. Severe Visceral Leishmaniasis Associated With COVID-19 and Complicated by Hemophagocytic Syndrome. Pediatr. Infect. Dis. J. 2022;41:e544–e545. doi: 10.1097/INF.0000000000003699. - DOI - PMC - PubMed
    1. Garazzino S., Vecchio A.L., Pierantoni L., Carducci F.I.C., Marchetti F., Meini A., Castagnola E., Vergine G., Donà D., Bosis S., et al. Epidemiology, clinical features and prognostic factors of pediatric SARS-CoV-2 infection: Results from an Italian multicenter study. Front. Pediatr. 2021;9:649358. doi: 10.3389/fped.2021.649358. - DOI - PMC - PubMed
    1. Cui X., Zhao Z., Zhang T., Guo W., Guo W., Zheng J., Zhang J., Dong C., Na R., Zheng L., et al. A systematic review and meta-analysis of children with coronavirus disease 2019 (COVID-19) J. Med Virol. 2020;93:1057–1069. doi: 10.1002/jmv.26398. - DOI - PMC - PubMed
    1. Alemayehu B., Alemayehu M. Leishmaniasis: A Review on Parasite, Vector and Reservoir Host. Health Sci. J. 2017;11:1. doi: 10.21767/1791-809X.1000519. - DOI
    1. Herwaldt B.L. Leishmaniasis. Lancet. 1999;354:1191–1199. doi: 10.1016/S0140-6736(98)10178-2. - DOI - PubMed

LinkOut - more resources