Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Sep 21;12(18):3343.
doi: 10.3390/plants12183343.

Amazonian Plants: A Global Bibliometric Approach to Petiveria alliacea L. Pharmacological and Toxicological Properties

Affiliations
Review

Amazonian Plants: A Global Bibliometric Approach to Petiveria alliacea L. Pharmacological and Toxicological Properties

Brenda Costa da Conceição et al. Plants (Basel). .

Abstract

Petiveria alliacea L. (Phytolaccaceae) holds significant importance in the Amazon region, where it has been traditionally utilized in folk medicine. In this study, we conducted a comprehensive bibliometric analysis using conventional metrics, combined with a critical content review of its pharmacological and toxicological properties, to identify gaps in the existing literature that require further investigation. Our investigation identified a total of 55 articles that met the inclusion criteria for this study. Remarkably, Brazil emerged as the primary contributor within the scope of this review, indicating a strong presence of research from this country. Furthermore, professional scientific societies have played a pivotal role in facilitating the dissemination of scientific findings through specialist journals, fostering the sharing of research work within the community. Analysis of keyword co-occurrence revealed that "Petiveria alliacea", "plant extract", and "guatemala" were the most frequently encountered terms, indicating their significance within the literature. In terms of study designs, in vivo and in vitro were the predominant types observed, highlighting their prevalence in this field of study. Our study also identified a lack in knowledge yet to be investigated.

Keywords: Petiveria alliacea; bibliometric analysis; medicinal plants; phamacological properties; toxicology.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Network visualization of authors with the number of publications (A), citations (B), and leading network of authors (C). There is a direct proportionality of the cluster size and the number of publications or citations.
Figure 2
Figure 2
Network visualization of the co-occurrence of the keywords used by the authors of the selected studies using the VOS viewer software. Clusters are highlighted by different colors. The node size represents the frequency of the keyword, and the lines reveal the connections between the keywords (A). The top 10 most frequent words are represented in panel (B), associated with their total link strength.
Figure 3
Figure 3
Worldwide distribution of selected articles (A) with the representation of countries from published articles (B), total number of citations (C), and citation density (D).
Figure 4
Figure 4
Historical series of publications by decade (A) and study types by year (B).
Figure 5
Figure 5
Schematic representation of the search strategy applied to retrieve selected articles.
Figure 6
Figure 6
Methodological strategy applied to perform the critical analysis.

Similar articles

Cited by

References

    1. Taylor J.L.S., Rabe T., McGaw L.J., Jäger A.K., Van Staden J. Towards the Scientific Validation of Traditional Medicinal Plants. Plant Growth Regul. 2001;34:23–37. doi: 10.1023/A:1013310809275. - DOI
    1. Zavala-Ocampo L.M., Aguirre-Hernández E., López-Camacho P.Y., Cárdenas-Vázquez R., Dorazco-González A., Basurto-Islas G. Acetylcholinesterase Inhibition and Antioxidant Activity Properties of Petiveria alliacea L. J. Ethnopharmacol. 2022;292:115239. doi: 10.1016/j.jep.2022.115239. - DOI - PubMed
    1. Hao D., Xiao P. Pharmaceutical Resource Discovery from Traditional Medicinal Plants: Pharmacophylogeny and Pharmacophylogenomics. Chin. Herb. Med. 2020;12:104–117. doi: 10.1016/j.chmed.2020.03.002. - DOI - PMC - PubMed
    1. Mustika A., Fatimah N., Sari G.M. The Self-Nanoemulsifying Drug Delivery System of Petiveria alliacea Extract Reduced the Homeostatic Model Assessment-Insulin Resistance Value, Interleukin-6, and Tumor Necrosis Factor-α Level in Diabetic Rat Models. Vet. World. 2021;14:3229–3234. doi: 10.14202/vetworld.2021.3229-3234. - DOI - PMC - PubMed
    1. Caballero-Serrano V., McLaren B., Carrasco J.C., Alday J.G., Fiallos L., Amigo J., Onaindia M. Traditional Ecological Knowledge and Medicinal Plant Diversity in Ecuadorian Amazon Home Gardens. Glob. Ecol. Conserv. 2019;17:e00524. doi: 10.1016/j.gecco.2019.e00524. - DOI

LinkOut - more resources