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. 2023 Sep 28;31(10):594.
doi: 10.1007/s00520-023-08063-0.

The moderating effect of self-efficacy between social constraints, social isolation, family environment, and depressive symptoms among breast cancer patients in China: a cross-sectional study

ZhiHui Gu  1 , MengYao Li  1 , Li Liu  1 , Yue Ban  1 , Hui Wu  2
Affiliations

The moderating effect of self-efficacy between social constraints, social isolation, family environment, and depressive symptoms among breast cancer patients in China: a cross-sectional study

ZhiHui Gu et al. Support Care Cancer. .

Abstract

Background: For female breast cancer patients, the psychological status after surgery, especially the social and family psychological-related factors, deserves more attention. This study analyzed the influence of social constraints, social support, social isolation, family conflict, and family emotion expression on depression. At the same time, this study conducted the relationship between the variables and the mechanism of action.

Methods: We conducted a cross-sectional study and 522 breast cancer patients finished questionnaires consisting of Self-Rating Depression Scale (SDS), General Self-Efficacy Scale (GSES), Multi-Dimensional Scale of Perceived Social Support (MSPSS), Social Constraints Scale-5 (SCS-5), Family Environment Scale (FES), and Lubben Social Network Scale (LSNS-6). Multivariable logical regression was used to explore influencing factors. Pearson's correlation, hierarchical regression, and simple slope analysis were conducted to verify the role of self-efficacy.

Results: 71.6% of patients had depressive symptoms. Family contradiction (OR = 10.086), social constraints (OR = 2.522), social isolation (OR = 2.507), and high blood glucose (OR = 2.156) were risk factors of depressive symptoms. Family emotional expression (OR = 0.480), family intimacy (OR = 0.235), and self-efficacy (OR = 0.246) were protective factors against depressive symptoms. The interactive items interpretation quantity were as follows: Contradiction*Self-efficacy (ΔR2 = 2.3%, P < 0.001), Emotional expression*Self-efficacy (ΔR2 = 2.6%, P < 0.001), Intimacy*Self-efficacy (ΔR2 = 1.0%, P = 0.018), Social constraints*Self-efficacy (ΔR2 = 1.0%, P = 0.008), Social networks*Self-efficacy (ΔR2 = 1.0%, P = 0.010), Blood Glucose*Self-efficacy (ΔR2 = 0.6%, P = 0.023). The influence of independent variables on depressive symptoms was gradually decreased in the low, mean, and high groups of self-efficacy.

Conclusion: Postoperative Chinese breast cancer survivors reported higher depressive symptoms. Social, family, and physiological factors could affect depressive symptoms, in which self-factor played moderator roles.

Keywords: Blood glucose; Family environment; Self-efficacy; Social constraints; Social isolation.

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References

    1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F (2021) Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71:209–249. https://doi.org/10.3322/caac.21660 - DOI - PubMed
    1. Guo R, Si J, Xue J, Su Y, Mo M, Yang B, Zhang Q, Chi W, Chi Y, Wu J (2019) Changing patterns and survival improvements of young breast cancer in China and SEER database, 1999-2017. Chin J Cancer Res 31:653–662. https://doi.org/10.21147/j.issn.1000-9604.2019.04.09 - DOI - PubMed - PMC
    1. Maajani K, Jalali A, Alipour S, Khodadost M, Tohidinik HR, Yazdani K (2019) The global and regional survival rate of women with breast cancer: a systematic review and meta-analysis. Clin Breast Cancer 19:165–177. https://doi.org/10.1016/j.clbc.2019.01.006 - DOI - PubMed
    1. Nakhlband A, Farahzadi R, Saeedi N, Barzegar H, Montazersaheb S, Soofiyani SR (2023) Bidirectional relations between anxiety, depression, and cancer: a review. Curr Drug Targets 24:118–130. https://doi.org/10.2174/1389450123666220922094403 - DOI - PubMed
    1. JavanBiparva A, Raoofi S, Rafiei S, Masoumi M, Doustmehraban M, Bagheribayati F, VaziriShahrebabak ES, NooraniMejareh Z, Khani S, Abdollahi B, AbediBafrajard Z, SotoudeBeidokhti S, Shojaei SF, Rastegar M, PashazadehKan F, NosratiSanjabad E, Ghashghaee A (2023) Global depression in breast cancer patients: systematic review and meta-analysis. PLoS One 18:e0287372. https://doi.org/10.1371/journal.pone.0287372 - DOI

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