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Case Reports
. 1986 Nov;81(11):1082-3.

Cloxacillin-induced cholestatic jaundice

F Konikoff, J Alcalay, J Halevy
  • PMID: 3776959
Case Reports

Cloxacillin-induced cholestatic jaundice

F Konikoff et al. Am J Gastroenterol. 1986 Nov.

Abstract

A case of cholestatic jaundice after cloxacillin treatment is presented. Hepatotoxicity due to the drug was confirmed by inadvertent rechallenge and strongly positive tests for macrophage migration inhibitory factor and mast cell degranulation. The recognition of cholestatic hepatotoxicity due to oxacillin derivatives should help to avoid unnecessary invasive procedures in the evaluation of this reversible condition.

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