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. 2023 Dec 7;73(1):16-46.
doi: 10.1136/gutjnl-2023-330029.

British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma

Simon M Rushbrook  1 , Timothy James Kendall  2   3 , Yoh Zen  4 , Raneem Albazaz  5 , Prakash Manoharan  6 , Stephen P Pereira  7 , Richard Sturgess  8 , Brian R Davidson  9 , Hassan Z Malik  10 , Derek Manas  11 , Nigel Heaton  12 , K Raj Prasad  13 , John Bridgewater  14 , Juan W Valle  15 , Rebecca Goody  16 , Maria Hawkins  17 , Wendy Prentice  18 , Helen Morement  19 , Martine Walmsley  20 , Shahid A Khan  21   22
Affiliations

British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma

Simon M Rushbrook et al. Gut. .

Abstract

These guidelines for the diagnosis and management of cholangiocarcinoma (CCA) were commissioned by the British Society of Gastroenterology liver section. The guideline writing committee included a multidisciplinary team of experts from various specialties involved in the management of CCA, as well as patient/public representatives from AMMF (the Cholangiocarcinoma Charity) and PSC Support. Quality of evidence is presented using the Appraisal of Guidelines for Research and Evaluation (AGREE II) format. The recommendations arising are to be used as guidance rather than as a strict protocol-based reference, as the management of patients with CCA is often complex and always requires individual patient-centred considerations.

Keywords: cholangiocarcinoma.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Histopathology of intrahepatic cholangiocarcinoma (iCCA). (A) Small duct iCCA shows an anastomosing tubular architecture. (B) In large duct iCCA, columnar cancer cells with intracytoplasmic mucus are arranged in a ductal structure against the background of fibrotic stroma.
Figure 2
Figure 2
Bismuth Corlette classification of location of biliary strictures.
Figure 3
Figure 3
Schematic Representation of the Memorial Sloan-Kettering Cancer Centre classification system.
Figure 4
Figure 4
Memorial Sloan-Kettering Cancer Centre postoperative prognostic nomogram. DSS, disease-specific survival.
See this image and copyright information in PMC

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