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. 2023:48:327-354.
doi: 10.1007/978-3-031-36785-4_12.

Clinical and Surgical Approach for Cerebral Cortical Dysplasia

Affiliations

Clinical and Surgical Approach for Cerebral Cortical Dysplasia

Marcelo Volpon Santos et al. Adv Tech Stand Neurosurg. 2023.

Abstract

The present article describes pathophysiological and clinical aspects of congenital malformations of the cerebral tissue (cortex and white matter) that cause epilepsy and very frequently require surgical treatment. A particular emphasis is given to focal cortical dysplasias, the most common pathology among these epilepsy-related malformations. Specific radiological and surgical features are also highlighted, so a thorough overview of cortical dysplasias is provided.

Keywords: Cortical dysplasia; Epilepsy; Epilepsy surgery; Malformations of cortical development; Outcome.

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References

    1. Otsuki T, Honda R, Takahashi A. Surgical management of cortical dysplasia in infancy and early childhood. Brain Dev. 2013;35(8):802–9. - PubMed - DOI
    1. Jamuar SS, Walsh CA. Genomic variants and variations in malformations of cortical development. Pediatr Clin N Am. 2015;62(3):571–85. - DOI
    1. Myers CT, Mefford HC. Advancing epilepsy genetics in the genomic era. Genome Med. 2015;7(1):91. - PubMed - PMC - DOI
    1. Pasquier B, Péoc'H M, Fabre-Bocquentin B, Bensaadi L, Pasquier D, Hoffmann D, Kahane P, Tassi L, Le Bas JF, Benabid AL. Surgical pathology of drug-resistant partial epilepsy. A 10-year-experience with a series of 327 consecutive resections. Epileptic Disord. 2002;4(2):99–119. - PubMed
    1. Fauser S, Essang C, Altenmüller DM. Long-term seizure outcome in 211 patients with focal cortical dysplasia. Epilepsia. 2015;56(1):66–76. - PubMed - DOI

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