Unusual paranasal sinus solitary neurofibroma and literature review

Abstract

Neurofibroma (NF) is a common benign peripheral neurogenic tumor that is rarely encountered in the paranasal sinus tract. In this report, we present a 55-year-old female who serendipitously discovered a maxillary sinus NF during a medical examination for a pulmonary nodule. The purpose of this article is to enhance medical practitioners' comprehension of paranasal sinus solitary NF by exploring cases, summarizing occurrences located in the paranasal sinus tract and conducting an organized review of paranasal sinus tract NF.

Figure 1.

Transverse MR imaging of the nasal sinus demonstrated a solid mass occupying her left maxillary sinus(white arrows), measuring approximately 45 mm × 36 mm × 26 mm, and exhibiting hypointensity on T1WI(a), inhomogeneous hyperintensity on T2WI(b) and fat-suppression sequence(c), and moderate hyperintensity on DWI(d).

Figure 2.

Axial non contrast-enhanced CT imaging(a) showed a round solid soft tissue mass(white arrows) in the left maxillary sinus with punctate calcification at its center(black arrow head). Contrast enhanced CT imaging(c and d) indicated mild uneven enhancement of the mass (an increase of about 5-10 HU); her maxillary sinus cavity was distended with bone resorption on its inner wall(d).

Figure 3.

Pathological section microscopy showed abundant tumor cells presenting multiple elongated spindle cells scattered in Wagner Meissner body (HE×100).