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Case Reports
. 2023 Sep 12;9(5):20230025.
doi: 10.1259/bjrcr.20230025. eCollection 2023 Oct.

Unusual paranasal sinus solitary neurofibroma and literature review

Xian Chun Yang  1 , Li Chen  1
Affiliations
Case Reports

Unusual paranasal sinus solitary neurofibroma and literature review

Xian Chun Yang et al. BJR Case Rep. .

Abstract

Neurofibroma (NF) is a common benign peripheral neurogenic tumor that is rarely encountered in the paranasal sinus tract. In this report, we present a 55-year-old female who serendipitously discovered a maxillary sinus NF during a medical examination for a pulmonary nodule. The purpose of this article is to enhance medical practitioners' comprehension of paranasal sinus solitary NF by exploring cases, summarizing occurrences located in the paranasal sinus tract and conducting an organized review of paranasal sinus tract NF.

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Figures

Figure 1.
Figure 1.
Transverse MR imaging of the nasal sinus demonstrated a solid mass occupying her left maxillary sinus(white arrows), measuring approximately 45 mm × 36 mm × 26 mm, and exhibiting hypointensity on T1WI(a), inhomogeneous hyperintensity on T2WI(b) and fat-suppression sequence(c), and moderate hyperintensity on DWI(d).
Figure 2.
Figure 2.
Axial non contrast-enhanced CT imaging(a) showed a round solid soft tissue mass(white arrows) in the left maxillary sinus with punctate calcification at its center(black arrow head). Contrast enhanced CT imaging(c and d) indicated mild uneven enhancement of the mass (an increase of about 5-10 HU); her maxillary sinus cavity was distended with bone resorption on its inner wall(d).
Figure 3.
Figure 3.
Pathological section microscopy showed abundant tumor cells presenting multiple elongated spindle cells scattered in Wagner Meissner body (HE×100).
See this image and copyright information in PMC

References

    1. Tall A, N’diaye C, Diom E-S, Thiam I. Solitary Neurofibroma originating from the posterior nasal septum: transnasal endoscopic resection. Eur Ann Otorhinolaryngol Head Neck Dis 2015; 132: 223–25. doi: 10.1016/j.anorl.2015.03.001 - DOI - PubMed
    1. Jain D, Chaudhary M, Patil S. Neurofibroma of the Maxillary antrum: A rare case. Contemp Clin Dent 2014; 5: 115–18. doi: 10.4103/0976-237X.128686 - DOI - PMC - PubMed
    1. Azani AB, Bishop JA, Thompson LDR. Sinonasal tract Neurofibroma: A Clinicopathologic series of 12 cases with a review of the literature. Head Neck Pathol 2015; 9: 323–33. doi: 10.1007/s12105-014-0593-x - DOI - PMC - PubMed
    1. Yap D, Fox H, Addams-Williams J. Unusual case of a Proptosed eye: isolated right Maxillary Neurofibroma. Case Rep Pathol 2016; 2016: 4294729. doi: 10.1155/2016/4294729 - DOI - PMC - PubMed
    1. Hachem RNA, Bared A, Zeitouni J, Younis RT. Single-stage total endoscopic resection of a Plexiform Neurofibroma of the Maxillary sinus in a child with type 1 Neurofibromatosis. Int J Pediatr Otorhinolaryngol 2010; 74: 426–29. doi: 10.1016/j.ijporl.2009.12.012 - DOI - PubMed

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