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. 2024 Jan;24(1):32-39.
doi: 10.1016/j.clml.2023.09.004. Epub 2023 Sep 15.

Creating Equitable and Inclusive Clinical Trials for Multiple Myeloma

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Free article

Creating Equitable and Inclusive Clinical Trials for Multiple Myeloma

Monique Hartley-Brown et al. Clin Lymphoma Myeloma Leuk. 2024 Jan.
Free article

Abstract

Black and Latino/Hispanic populations are disproportionately impacted by multiple myeloma (MM) in the United States and are underrepresented in many clinical trials. The Multiple Myeloma Research Foundation sponsored a 1-day workshop of 46 experts spanning the ecosystem of MM research and care, including government, academia, nonprofits, pharma/biotech, community partners, and retail pharmacy. Specific, tangible steps to overcome the well-documented barriers to improving the diversity and inclusivity of clinical trials were discussed, including broadening inclusion/exclusion criteria, reducing the financial and other burdens of trial participants, selecting diverse study sites, including implicit bias training, and taking steps to empower patients.

Keywords: Clinical trial; Diversity; Equity; Inclusivity; Multiple myeloma.

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Conflict of interest statement

Disclosure Monique Hartley-Brown: Advisory board participation for Abbvie, BMS, Celgene, GSK, Janssen, Karyopharm, Sanofi. Research funding from BMS /Celgene, GSK, Sanofi. Craig E. Cole: Discussion Board/consultation for Pfizer, Sanofi, Asta-Zenca, Abbvie, Genentech. Research: GSK. Pamela Price: None to report. Michael Andreini: Employee of MMRF. George Mulligan: Employee of MMRF. Anne Quinn Young: Employee of MMRF. Hearn Jay Cho: Employee of MMRF. Research support from Takeda, BMS/Celgene.

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