Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Dec;19(12):681-682.
doi: 10.1038/s41574-023-00910-8.

Stem cell-derived islet therapy: is this the end of the beginning?

Veronica A Cochrane  1 , Matthias Hebrok  2   3
Affiliations

Stem cell-derived islet therapy: is this the end of the beginning?

Veronica A Cochrane et al. Nat Rev Endocrinol. 2023 Dec.
No abstract available

PubMed Disclaimer

References

    1. Banting, F. G. Nobel lecture: diabetes and insulin. The Nobel Prize https://www.nobelprize.org/prizes/medicine/1923/banting/lecture/ (1925).
    1. Balboa, D. et al. Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells. Nat. Biotechnol. 40, 1042–1055 (2022). - DOI - PubMed - PMC
    1. Davis, J. C. et al. Glucose response by stem cell-derived β cells in vitro is inhibited by a bottleneck in glycolysis. Cell Rep. 31, 107623 (2020). - DOI - PubMed - PMC
    1. Augsornworawat, P. et al. Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification. Nat. Cell Biol. 25, 904–916 (2023). - DOI - PubMed - PMC
    1. Zhu, H. et al. Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes. Dev. Cell 58, 727–743.e11 (2023). - DOI - PubMed

LinkOut - more resources