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. 2023 Apr-Jun;49(2):237-243.
doi: 10.12865/CHSJ.49.02.237. Epub 2023 Jun 30.

Statical Association between Clinical and Histopathological Parameters for Keratinocyte Carcinomas

Alin Cristian Badiu  1 , Cristiana Eugenia Simionescu  2 , Alex Emilian Stepan  2 , Claudiu Mărgăritescu  2 , Mirela Marinela Florescu  2 , Bianca Cătălina Andreiana  2 , Anne-Marie Badiu  2 , Oana Iulia Crețu  1 , Andrei Muraru  1 , Cristina Geormăneanu  3 , Raluca Niculina Ciurea  2
Affiliations

Statical Association between Clinical and Histopathological Parameters for Keratinocyte Carcinomas

Alin Cristian Badiu et al. Curr Health Sci J. 2023 Apr-Jun.

Abstract

The most common tumor of the western world is comprised of forms of non-melanoma skin cancers, previously known as keratinocyte carcinomas (KCs) The purpose of this study was to determine de incidence of non-melanoma skin tumors and the relationship between histopathological risk factors in patients with skin cancers. The study was composed from 332 cases of skin malignancies for which clinical and histopathological aggressivity factors were statistically analyzed through comparison tests and also stored digitally. For basal cell carcinoma (BCC) statistical analysis indicated significant relationships between pT category and gender, tumor size, ulceration, depth of invasion and positive resection limits. For squamous cell carcinoma (SCC) statistical analysis indicated significant relationships between pT category and tumor size, depth of invasion and positive resection limits. Clinical and histological analysis of certain characteristics of the above-mentioned skin cancers is an essential step in documenting and improving both prognosis and therapy standards.

Keywords: Keratinocyte carcinomas; clinical parameters; histopathological parameters.

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Conflict of interest statement

None to declare.

Figures

Figure 1
Figure 1
Cases distribution depending on pT category and tumor size (A), depth of invasion (B) and invasion of resection limits (C).
Figure 2
Figure 2
Cases distribution depending on pT category and gender (A), tumor size (B), ulceration (C), depth of invasion (D) and resection limits (E).
See this image and copyright information in PMC

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