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. 1986 Oct;64(2):277-81.
doi: 10.1111/j.1365-2141.1986.tb04120.x.

Circulating transferrin receptor in human serum

Y Kohgo, T Nishisato, H Kondo, N Tsushima, Y Niitsu, I Urushizaki

Circulating transferrin receptor in human serum

Y Kohgo et al. Br J Haematol. 1986 Oct.

Abstract

Circulating transferrin receptor has been detected in human serum with a sensitive immunoassay. The mean concentrations of the serum transferrin receptor in healthy males and females were 251 +/- 94 (mean +/- SD) ng/ml and 256 +/- 99 ng/ml, respectively. The serum receptor concentration in patients with haematological malignancies, including acute leukaemia, multiple myeloma and malignant lymphoma, varied widely, from normal to 1100 ng/ml. A single band with an approximate molecular weight between 80,000 and 100,000 daltons was obtained by polyacrylamide gel electrophoresis-immunoblotting analysis of serum.

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