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. 2023;24(2):143-150.
doi: 10.22099/IJVR.2023.46494.6674.

Pentraxin-3, endothelin-1, some biochemical parameters and hematology in bovine respiratory disease complex

Affiliations

Pentraxin-3, endothelin-1, some biochemical parameters and hematology in bovine respiratory disease complex

E Akyüz et al. Iran J Vet Res. 2023.

Abstract

Abstract.

Background: Infectious bovine respiratory disease complex (BRDC) is one of the world's major livestock problems.

Aims: The study aimed to determine the diagnostic importance of pentraxin-3, endothelin-1, clinical biochemistry, and hematological parameters in infectious BRDC.

Methods: Animals in this study were Simmental breed, 1-7 years old, untreated, and healthy and BRDC cattle (40 cattle with BRDC in the disease group, and 10 healthy cattle in the control group). Clinical findings such as general posture, respiratory rate per minute, rectal temperature, heart rate per minute, and mental posture of the diseased cattle were recorded. Blood samples were taken from the jugular vein only once from all cattle. Complete blood count from blood samples was measured in an automatic complete blood count device, biochemical parameters in an autoanalyzer, and pentraxin-3 and endothelin-1 were measured by ELISA method.

Results: Rectal temperature, respiratory and pulse rates per minute, total leukocyte count, gamma-glutamyl transferase, urea, total bilirubin, lactate dehydrogenase, creatine kinase, pentraxin-3 and endothelin-1 concentrations were found to be statistically higher in BRDC group than those in the control group (P<0.001).

Conclusion: Pentraxin-3 and endothelin-1 levels were statistically significantly higher in the BRDC group compared to the control group. As a result, pentraxin-3 and endothelin-1 were found to be diagnostically important in cattle diagnosed with BRDC.

Keywords: BRDC; Cattle; Endothelin-1; Hematology; Pentraxin-3.

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Conflict of interest statement

The authors have declared that no conflicts of interest are associated with this study or its results.

Figures

Fig. 1
Fig. 1
Comparison of mean values of serum pentraxin-3 and endothelin-1 concentrations between BRDC and control groups. (A) Comparison of mean serum pentraxin-3 concentration of cattle in BRDC and control groups (P<0.001), and (B) Comparison of mean serum endothelin-1 concentration between BRDC and control groups (P<0.001). BRDC: Bovine respiratory disease complex
Fig. 2
Fig. 2
Radiographic image from cattle with BRDC. Radiopaque appearance was dominant in all lung areas. The radiopaque image was observed to become more radiolucent towards the caudal, where the opacity increase was especially in the cranial lobes
Fig. 3
Fig. 3
RT-PCR gel electrophoresis of BHV-1 some positive samples. M: Marker, PC: Positive control (468 bp), positive samples; 1, 4, 7, 10, 11, 14, 15, 17, 19, 22

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