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Review
. 2023 Sep 18:15:1259190.
doi: 10.3389/fnagi.2023.1259190. eCollection 2023.

Multimodal magnetic resonance imaging on brain structure and function changes in subjective cognitive decline: a mini-review

Jinhuan Yue  1   2 , Shengwang Han  3 , Ang Li  4 , Zeyi Wei  5 , Danna Cao  6 , Shenglan Gao  5 , Xiaoling Li  6 , Guanhu Yang  7 , Qinhong Zhang  1   8
Affiliations
Review

Multimodal magnetic resonance imaging on brain structure and function changes in subjective cognitive decline: a mini-review

Jinhuan Yue et al. Front Aging Neurosci. .

Abstract

Subjective cognitive decline (SCD) is the initial stage of Alzheimer's disease (AD). Early identification of SCD and its risk factors is of great importance for targeted interventions and for delaying the onset of AD. We reviewed the relevant literature on structural magnetic resonance imaging (sMRI), diffusion tensor imaging (DTI), functional magnetic resonance imaging (fMRI), and other techniques regarding SCD research in recent years. This study applied sMRI and fMRI techniques to explore abnormal brain structures and functions, which may help provide a basis for SCD diagnosis.

Keywords: brain function; brain structure; magnetic resonance imaging; multimodal; subjective cognitive decline.

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Conflict of interest statement

JY and QZ are employed by Shenzhen Frontiers in Chinese Medicine Research Co., Ltd. and AL is employed by Servier (Beijing) Pharmaceutical Research & Development CO. Ltd. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Multimodal MRI of brain structure and function in SCD.
See this image and copyright information in PMC

References

    1. Achard S., Bullmore E. (2007). Efficiency and cost of economical brain functional networks. PLoS Comput. Biol. 3:e17. doi: 10.1371/journal.pcbi.0030017, PMID: - DOI - PMC - PubMed
    1. Albert M. S., DeKosky S. T., Dickson D., Dubois B., Feldman H. H., Fox N. C., et al. . (2011). The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 7, 270–279. doi: 10.1016/j.jalz.2011.03.008, PMID: - DOI - PMC - PubMed
    1. Arvanitakis Z., Shah R. C., Bennett D. A. (2019). Diagnosis and Management of Dementia: review. JAMA 322, 1589–1599. doi: 10.1001/jama.2019.4782, PMID: - DOI - PMC - PubMed
    1. Brown H. D., Woodall R. L., Kitching R. E., Baseler H. A., Morland A. B. (2016). Using magnetic resonance imaging to assess visual deficits: a review. Ophthalmic. Physiol. Opt. 36, 240–265. doi: 10.1111/opo.12293, PMID: - DOI - PMC - PubMed
    1. Fu Z., Zhao M., He Y., Wang X., Lu J., Li S., et al. . (2021). Divergent connectivity changes in gray matter structural covariance networks in subjective cognitive decline, amnestic mild cognitive impairment, and Alzheimer's disease. Front. Aging Neurosci. 13:686598. doi: 10.3389/fnagi.2021.686598, PMID: - DOI - PMC - PubMed

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