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Case Reports
. 2023 Oct 5;389(14):1321-1326.
doi: 10.1056/NEJMcps2304154.

Digging into the Histology

Raghavendra Paknikar  1 , Lindsay Alpert  1 , Russell D Cohen  1 , Benjamin Shogan  1 , Dejan Micic  1
Affiliations
Case Reports

Digging into the Histology

Raghavendra Paknikar et al. N Engl J Med. .
No abstract available

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Figures

Figure 1:
Figure 1:. Chest Radiograph.
An anteroposterior chest radiograph shows diffuse reticulonodular opacities.
Figure 2:
Figure 2:. Abdominal Radiograph.
An anteroposterior abdominal radiograph obtained with patient in the supine position shows a focally dilated loop of colon.
Figure 3:
Figure 3:. CT of the Abdomen and Pelvis.
CT of the abdomen and pelvis was performed after the adminstraion of oral contrast material. An axial iamge of the abdomen (Panel A) shows a punctate focus of pneumoperitoneum anterior to the liver, with small volume perihepatic ascites. A coral image of the abdomen and pelvis (Panel B) shows diffuse wall thickening in the rectosigmoid colon and extravasation of extraluminal contrast material (arrow) into the area adjucent to the sigmoid colon, with layering of the contrast material, findings that are thought to indicate a perforation.
Figure 4:
Figure 4:. Resection Specimens.
Gross examination of resection specimen of the colon (Panel A) reveals ulceration (asterisks). Hematoxylin and eosin staining (Panel B) shows ulceration with transmural granuloma. At higher power (Panel C), necrotizing granulomas are seen. Grocott-Gomori methenamine silver staining (Panel D) highlights clusters of small, ovoid yeast forms that are consistent with Histoplasma capsulatum.
See this image and copyright information in PMC

References

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Publication types