Targeting expanded trinucleotide repeats

Comment

Sarah Crunkhorn. Nat Rev Drug Discov. 2023 Nov.

. 2023 Nov;22(11):873.

doi: 10.1038/d41573-023-00160-3.

No abstract available

Comment on

A cyclic pyrrole-imidazole polyamide reduces pathogenic RNA in CAG/CTG triplet repeat neurological disease models.
Ikenoshita S, Matsuo K, Yabuki Y, Kawakubo K, Asamitsu S, Hori K, Usuki S, Hirose Y, Bando T, Araki K, Ueda M, Sugiyama H, Shioda N. Ikenoshita S, et al. J Clin Invest. 2023 Nov 15;133(22):e164792. doi: 10.1172/JCI164792. J Clin Invest. 2023. PMID: 37707954 Free PMC article.

1. Ikenoshita, S. et al. A cyclic pyrrole-imidazole polyamide reduces pathogenic RNA in CAG/CTG triplet repeat neurological disease models. J. Clin. Invest. https://doi.org/10.1172/JCI164792 (2023)