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. 2023 Sep 30;26(3):265-275.
doi: 10.3831/KPI.2023.26.3.265.

Antibacterial Activity of Selected Fruit Juices against Multidrug-Resistant Bacterial Pathogens Involved in Urinary Tract and Sexually Transmitted Infections among Tribal Women in Madhya Pradesh, India

Poonam Sharma  1 , Juhi  1 , Vaishali Halwai  1 , Sainivedita Rout  1 , Rambir Singh  2
Affiliations

Antibacterial Activity of Selected Fruit Juices against Multidrug-Resistant Bacterial Pathogens Involved in Urinary Tract and Sexually Transmitted Infections among Tribal Women in Madhya Pradesh, India

Poonam Sharma et al. J Pharmacopuncture. .

Abstract

Objectives: The aim of this study was to evaluate the effect of fruit juices on Multi-Drug Resistant (MDR) bacterial pathogens involved in Urinary Tract Infections (UTIs) and Sexually Transmitted Infections (STIs) among tribal women in the district Anuppur, Madhya Pradesh, India.

Methods: Fresh juices of lemon (Citrus limon), amla/Indian gooseberry (Phyllanthus emblica), pineapple (Ananas comosus), mosambi/sweet lime (Citrus limetta), orange (Citrus sinensis), kiwi (Actinidia deliciosa), and pomegranate (Punica granatum) fruits were evaluated for in vitro antibacterial activity against bacterial pathogens involved in UITs and STIs among tribal women. Physico-chemical analysis of fresh fruits was also carried out by measuring the pH, moisture, protein, fat, crude fibre, carbohydrate, and ascorbic acid content.

Results: Lemon and amla juice showed better antibacterial activity against the pathogens as compared to other juices. MIC results fruit juices against UTIs and STIs pathogens vary depending on the specific pathogen and juice chemical constituents. The physico-chemical analysis showed that the moisture content was highest in mosambi (90%), followed by orange (87%). Ascorbic acid content was found highest in amla (540 mg/100 g), followed by kiwi (90.3 mg/100 g). Pomegranate showed highest concentration of carbohydrate (15.28 g/100 g), fat (1.28 g/100 g), and protein (1.65 g/100 g). Lemon juice had lowest pH of 2.20, followed by amla 2.67.

Conclusion: The lemon juice showed highest antibacterial activity against MDR bacterial pathogens involved in UTIs and STIs among tribal women in district Anuppur, Madhya Pradesh, India. The low pH of lemon may be responsible for its high antibacterial activity as compared to other juices.

Keywords: antibacterial activity; fruit juices; multi-drug resistant; sexually transmitted infection; uropathogens.

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Conflict of interest statement

CONFLICTS OF INTEREST The authors declare that there is no conflict of interest.

Figures

Figure 1
Figure 1
Growth of UTI and STI pathogens on specific culture media, AST, and antibacterial activity of fruits juices.
Figure 2
Figure 2
Minimum Inhibitory Concentration (MIC) of lemon and amla juices against N. gonorrhoea.
Figure 3
Figure 3
Possible mechanism of antibacterial activity of lemon, amla and pineapple fruit juices.
See this image and copyright information in PMC

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References

    1. Mah ND, Birmingham AR, Treu CN, Bodkin RP, Awad NI, Acquisto NM. Sexually transmitted infection review for the acute care pharmacist. J Pharm Pract. 2020;33(1):63–73. doi: 10.1177/0897190018764567. - DOI - PubMed
    1. Sarkar S, Patra AC, Srinivas P, Ghosh A, Kushbaha G, Saha S. Pattern of sexually transmitted infections: a profile from a rural- and tribal-based sexually transmitted infections clinic of a tertiary care hospital of Eastern India. J Family Med Prim Care. 2018;7(5):1042–6. doi: 10.4103/jfmpc.jfmpc_80_17. - DOI - PMC - PubMed
    1. Behzadi P, Behzadi E, Pawlak-Adamska EA. Urinary tract infections (UTIs) or genital tract infections (GTIs)? It's the diagnostics that count. GMS Hyg Infect Control. 2019;14:Doc14. doi: 10.3205/dgkh000320. - DOI - PMC - PubMed
    1. Bhalla P, Sethi K, Reddy BS, Mathur MD. Antimicrobial susceptibility and plasmid profile of Neisseria gonorrhoeae in India (New Delhi) Sex Transm Infect. 1998;74(3):210–2. doi: 10.1136/sti.74.3.210. - DOI - PMC - PubMed
    1. Ray K, Bala M, Kumar J, Misra RS. Trend of antimicrobial resistance in Neisseria gonorrhoeae at New Delhi, India. Int J STD AIDS. 2000;11(2):115–8. doi: 10.1177/095646240001100209. - DOI - PubMed

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