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Comment
. 2024 Feb;21(2):65-66.
doi: 10.1038/s41585-023-00826-y.

Unlocking the mystery of the human Y chromosome

Miguel G Rojas  1 , Edoardo Pozzi  1 , Ranjith Ramasamy  2
Affiliations
Comment

Unlocking the mystery of the human Y chromosome

Miguel G Rojas et al. Nat Rev Urol. 2024 Feb.
No abstract available

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Comment on

  • Assembly of 43 human Y chromosomes reveals extensive complexity and variation.
    Hallast P, Ebert P, Loftus M, Yilmaz F, Audano PA, Logsdon GA, Bonder MJ, Zhou W, Höps W, Kim K, Li C, Hoyt SJ, Dishuck PC, Porubsky D, Tsetsos F, Kwon JY, Zhu Q, Munson KM, Hasenfeld P, Harvey WT, Lewis AP, Kordosky J, Hoekzema K; Human Genome Structural Variation Consortium (HGSVC); O'Neill RJ, Korbel JO, Tyler-Smith C, Eichler EE, Shi X, Beck CR, Marschall T, Konkel MK, Lee C. Hallast P, et al. Nature. 2023 Sep;621(7978):355-364. doi: 10.1038/s41586-023-06425-6. Epub 2023 Aug 23. Nature. 2023. PMID: 37612510 Free PMC article.

References

    1. Rhie, A. et al. The complete sequence of a human Y chromosome. Nature https://doi.org/10.1038/s41586-023-06457-y (2023). - DOI - PubMed - PMC
    1. Wilson, M. A. The Y chromosome and its impact on health and disease. Hum. Mol. Genet. 30, R296–R300 (2021). - DOI - PubMed - PMC
    1. Porubsky, D. et al. Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders. Cell 185, 1986–2005.e26 (2022). - DOI - PubMed - PMC
    1. Wenger, A. M. et al. Accurate circular consensus long-read sequencing improves variant detection and assembly of a human genome. Nat. Biotechnol. 37, 1155–1162 (2019). - DOI - PubMed - PMC
    1. Jain, M. et al. Nanopore sequencing and assembly of a human genome with ultra-long reads. Nat. Biotechnol. 36, 338–345 (2018). - DOI - PubMed - PMC

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