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Review
. 2023 Nov;31(4):443-452.
doi: 10.1016/j.fsc.2023.06.009. Epub 2023 Aug 12.

Translational Biochemistry of the Skin

Affiliations
Review

Translational Biochemistry of the Skin

Lindsey Voller et al. Facial Plast Surg Clin North Am. 2023 Nov.

Abstract

Understanding translational biochemistry of the skin is an essential component in mastering non-invasive aesthetic treatments. Collagen is the most abundant protein in the animal kingdom and plays a significant role in maintaining structural function in biologically healthy human skin. Collagen degradation and synthesis occurs throughout human life. Upregulation of collagen synthesis remains the mainstay of non-invasive aesthetic skin treatments. Elastin is a smaller yet significant component in the skin's ability to maintain biologically healthy stretch and recoil. Multi-Omics represents a relatively nascent field in the optimization and development of therapies aimed at the aesthetic improvement of the skin.

Keywords: Collagen; Degradation; Elastin; Synthesis; Wound healing.

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