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Review
. 2023 Nov;33(4):411-419.
doi: 10.1016/j.thorsurg.2023.04.004. Epub 2023 May 16.

Liquid Biopsy as an Adjunct to Lung Screening Imaging

Nathaniel Deboever  1 , Edwin J Ostrin  2 , Mara B Antonoff  3
Affiliations
Review

Liquid Biopsy as an Adjunct to Lung Screening Imaging

Nathaniel Deboever et al. Thorac Surg Clin. 2023 Nov.

Abstract

Current lung cancer screening protocols use low-dose computed tomography scans in selected high-risk individuals. Unfortunately, utilization is low, and the rate of false-positive screens is high. Peripheral biomarkers carry meaningful promise in diagnosing and monitoring cancer with added potential advantages reducing invasive procedures and improving turnaround time. Herein, the use of such blood-based assays is considered as an adjunct to further utilization and accuracy of lung cancer screening.

Keywords: Disease monitoring; Liquid biopsy; Low-dose computed tomography scan; Lung cancer screening.

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