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. 2023 Sep 6;15(9):e44772.
doi: 10.7759/cureus.44772. eCollection 2023 Sep.

Comparison of Intracervical Foley's Catheter With Vaginal Misoprostol Versus Intravaginal Misoprostol Alone for Cervical Ripening and Induction of Labor

Nivedita A Kadu  1 , Shobha Shiragur  1
Affiliations

Comparison of Intracervical Foley's Catheter With Vaginal Misoprostol Versus Intravaginal Misoprostol Alone for Cervical Ripening and Induction of Labor

Nivedita A Kadu et al. Cureus. .

Abstract

Introduction Induction of labor implies stimulation of contractions before the spontaneous onset of labor, with or without membranes. Augmentation refers to the enhancement of spontaneous contractions that are considered inadequate because of failed cervical and fetal descent. This study compared the effectiveness of intracervical Foley catheter insertion and vaginal misoprostol versus only vaginal misoprostol in the induction of labor and other outcomes relted to it. Methods The present study was a randomized controlled trial that included 148 women divided into two groups: (i) Group A, which received intracervical Foley catheter insertion and vaginal misoprostol (25 µg), and (ii) Group B, which received intravaginal administration of tablet misoprostol (25 µg) alone. We compared the median time from the time of induction to vaginal delivery, incidence of cesarean delivery, chorioamnionitis, puerperal infection, uterine tachysystole, neonatal information at delivery, and discharge status (i.e., birth weight, neonatal intensive care unit (NICU) admission, and neonatal death) between groups. Results We found that the rates of puerperal infection (n=36; 48.6%) and meconium-stained amniotic fluid (n=45; 60.8%) were higher in Group B than in Group A (n=20; 27.0% and n=25; 33.8%, respectively), which were statistically significant differences (p=0.0066 and p=0.0009, respectively). In addition, NICU admission was higher in Group B (n=47; 63.5%) than in Group A (n=30; 40.5%), which was a statistically significant difference (p=0.0051). Conclusion An intracervical Foley catheter with 25 µg of misoprostol was more effective for induction of labor than 25 µg of intravaginal misoprostol alone every six hours for a maximum of four doses in terms of induction to delivery interval, meconium-stained amniotic fluid, mode of delivery, intrapartum complications, and puerperal infection.

Keywords: augmentation; bishop score; cervical ripening; foley's catheter; induction of labour; meconium stained amniotic fluid; misoprostol.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Flow chart of the study
PROM: premature rupture of membranes
See this image and copyright information in PMC

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References

    1. Williams Obstetrics, 25th Edition. Australia: McGraw-Hill Education; 2018. Induction of labour and cervical ripening.
    1. A randomized controlled trial comparing vaginal misoprostol versus Foley catheter plus oxytocin for labor induction. Moraes Filho OB, Albuquerque RM, Cecatti JG. Acta Obstet Gynecol Scand. 2010;89:1045–1052. - PubMed
    1. Who Recommendations on Induction of Labour, at or Beyond Term. Geneva, Switzerland: World Health Organization; 2022. WHO Guidelines Approved by the Guidelines Review Committee. WHO Recommendations: Induction of Labor at or beyond Term. World Health Organization.
    1. Concurrent use of intracervical foleys catheter plus vaginal misoprostol versus vaginal misoprostol alone for induction of labour. Gilani S, Hanif M, Mazhar SB, Saeed N. https://jsogp.net/index.php/jsogp/article/view/184 J Soc Obstet Gynaecol Pak. 2018;8:189–193.
    1. Profiling cervical ripening for induction of labour with Foley’s balloon catheter in Ebonyi state, Nigeria: a randomized controlled trial. Adiele NA, Mgbafulu CC, Ikeotuonye AC, et al. https://www.msjonline.org/index.php/ijrms/article/view/10272 Int J Res Med Sci. 2022;10:22.

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