Excitation-contraction coupling in the myocardium of hibernating chipmunks
- PMID: 3780943
- DOI: 10.1007/BF01946394
Excitation-contraction coupling in the myocardium of hibernating chipmunks
Abstract
In the myocardium of nonhibernating chipmunks, replacing external Ca by Sr markedly prolongs the action potential plateau with an increase in contraction, while in preparations from hibernating animals this procedure inhibits both responses. Pretreatment with 4-aminopyridine causes a prolongation of the action potential plateau by Sr in hibernating animals.
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