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. 2023 Oct 6;11(9):E920-E927.
doi: 10.1055/a-2005-6934. eCollection 2023 Sep.

Retrospective comparison of G-EYE balloon-colonoscopy with standard colonoscopy for increased adenoma detection rate and reduced polyp removal time

Affiliations

Retrospective comparison of G-EYE balloon-colonoscopy with standard colonoscopy for increased adenoma detection rate and reduced polyp removal time

Ralf Kiesslich et al. Endosc Int Open. .

Abstract

Background and study aims The newly introduced G-EYE colonoscope (G-EYE) employs a balloon, installed at the bending section of a standard colonoscope (SC), for increasing adenoma detection and stabilizing the colonoscope tip during intervention. This retrospective work explores the effect of introducing G-EYE into an SC endoscopy room, in terms of adenoma detection and polyp removal time. Patients and methods This was a single-center, retrospective study. Historical data from patients who underwent colonoscopy prior to, and following, introduction of G-EYE into a particular endoscopy room were collected and analyzed to determine adenoma detection rate (ADR), adenoma per patient (APP), and polyp removal time (PRT), in each of the SC and G-EYE groups. Results Records of 1362 patients who underwent SC and 1433 subsequent patients who underwent G-EYE colonoscopy in the same endoscopy unit by the same endoscopists were analyzed. Following G-EYE introduction, overall ADR increased by 37.5 % ( P < 0.0001) from 39.2 % to 53.9 %, the serrated adenoma rate increased by 47.3 % from 27.9 % to 41.1 % ( P < 0.0001), and the APP increased by 50.6 % from 0.79 to 1.19 ( P < 0.0001). The number of advanced adenomas increased by 32.7 %, from 19.6 % to 26.0 % of all adenomas ( P < 0.0001). With G-EYE, average PRT was reduced overall by 29.5 % ( P < 0.0001), and particularly for endoscopic mucosal resection (EMR) by 37.5 % for polyps measuring ≥ 5 mm to ≤ 20 mm ( P < 0.0001) and by 29.4 % for large polyps > 20 mm ( P < 0.0001). Conclusions Introduction of G-EYE to an SC endoscopy room yielded considerable increase in ADR and notable reduction in PRT, particularly with the EMR technique. G-EYE balloon colonoscopy might increase the effectiveness of colorectal cancer screening and surveillance colonoscopy, and can shorten the time of endoscopic intervention.

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Conflict of interest statement

Competing interests The authors declare that they have no conflict of interest..

Figures

Fig. 1
Fig. 1
Left: G-EYE System. Right: G-EYE balloon integrated on a standard colonoscope NaviAid SPARK 2 C inflation system.
Fig. 2
Fig. 2
EMR time distribution histograms for SC and G-EYE, smoothed using Kernel estimation for polyps a ≥ 5 mm to ≤ 20 mm and b > 20 mm.

References

    1. Cancer Facts & Figures 2019. Atlanta: American Cancer Society 2019. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-... https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-...
    1. Levin B, Lieberman D A, McFarland B et al.Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer and the American College of Radiology. CA Cancer J Clin. 2008;58:130–160. - PubMed
    1. Cooper G S, Chak A, Koroukian S. The polyp detection rate of colonoscopy: a national study of medicare beneficiaries. Am J Med. 2005;118:1413. - PubMed
    1. Lieberman D A, Rex D K, Winawer S J et al.Guidelines for colonoscopy surveillance after screening and polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer. Gastroenterology. 2012;143:844–857. - PubMed
    1. Zauber A G, Winawer S J, O’Brien M J et al.Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med. 2012;366:687–696. - PMC - PubMed