Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Nov-Dec;89(6):101313.
doi: 10.1016/j.bjorl.2023.101313. Epub 2023 Aug 28.

Brazilian Society of Otology task force - Vestibular Schwannoma ‒ evaluation and treatment

Vagner Antonio Rodrigues Silva  1 , Joel Lavinsky  2 , Henrique Furlan Pauna  3 , Melissa Ferreira Vianna  4 , Vanessa Mazanek Santos  5 , Cláudio Márcio Yudi Ikino  6 , André Luiz Lopes Sampaio  7 , Paula Tardim Lopes  8 , Pauliana Lamounier  9 , André Souza de Albuquerque Maranhão  10 , Vitor Yamashiro Rocha Soares  11 , José Fernando Polanski  12 , Mariana Moreira de Castro Denaro  13 , Carlos Takahiro Chone  14 , Ricardo Ferreira Bento  8 , Arthur Menino Castilho  15
Affiliations
Review

Brazilian Society of Otology task force - Vestibular Schwannoma ‒ evaluation and treatment

Vagner Antonio Rodrigues Silva et al. Braz J Otorhinolaryngol. 2023 Nov-Dec.

Abstract

Objective: To review the literature on the diagnosis and treatment of vestibular schwannoma.

Methods: Task force members were educated on knowledge synthesis methods, including electronic database search, review and selection of relevant citations, and critical appraisal of selected studies. Articles written in English or Portuguese on vestibular schwannoma were eligible for inclusion. The American College of Physicians' guideline grading system and the American Thyroid Association's guideline criteria were used for critical appraisal of evidence and recommendations for therapeutic interventions.

Results: The topics were divided into 2 parts: (1) Diagnosis - audiologic, electrophysiologic tests, and imaging; (2) Treatment - wait and scan protocols, surgery, radiosurgery/radiotherapy, and systemic therapy.

Conclusions: Decision making in VS treatment has become more challenging. MRI can diagnose increasingly smaller tumors, which has disastrous consequences for the patients and their families. It is important to develop an individualized approach for each case, which highly depends on the experience of each surgical team.

Keywords: Auditory brain stem implants; Cochlear implant; Hearing loss, sensorineural; Neurofibromatosis 2; Neuroma, acoustic; Radiotherapy; Single sided deafness; Surgery; Vestibular schwannoma.

PubMed Disclaimer

Figures

Figure 1
Figure 1
(A) Small intracanalicular tumor; (B) Small tumor with protrusion into the cerebellopontine angle; no contact with the brainstem; (C) Tumor occupying the cerebellopontine cistern with no brainstem displacement; (D) Large tumor with brainstem and cranial nerve displacement.
Figure 2
Figure 2
A large vestibular schwannoma in the right CPA.
See this image and copyright information in PMC

References

    1. Babu R., Sharma R., Bagley J.H., Hatef J., Friedman A.H., Adamson C. Vestibular schwannomas in the modern era: epidemiology, treatment trends, and disparities in management. J Neurosurg. 2013;119:121–130. - PubMed
    1. Jeyakumar A., Seth R., Brickman T.M., Dutcher P. The prevalence and clinical course of patients with’ incidental’ acoustic neuromas. Acta Otolaryngol. 2007;127:1051–1057. - PubMed
    1. Ostrom Q.T., Gittleman H., Liao P., Vecchione-Koval T., Wolinsky Y., Kruchko C., et al. CBTRUS Statistical Report: primary brain and other central nervous system tumors diagnosed in the United States in 2010–2014. Neuro Oncol. 2017;19:v1–v88. - PMC - PubMed
    1. Xenellis J.E., Linthicum F.H. On the myth of the glial/schwann junction (Obersteiner-Redlich zone): origin of vestibular nerve schwannomas. Otol Neurotol. 2003;24:1. - PubMed
    1. Komatsuzaki A., Tsunoda A. Nerve origin of the acoustic neuroma. J Laryngol Otol. 2001;115:376–379. - PubMed

MeSH terms