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Editorial
. 2023 Oct 6;69(8):e2023D698.
doi: 10.1590/1806-9282.2023D698. eCollection 2023.

Use of intra-articular hyaluronic acid in knee osteoarthritis or osteoarthritis

Affiliations
Editorial

Use of intra-articular hyaluronic acid in knee osteoarthritis or osteoarthritis

Mauricio Anhesini et al. Rev Assoc Med Bras (1992). .
No abstract available

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Conflict of interest statement

Conflicts of interest: the authors declare there is no conflicts of interest.

Figures

Figure 1.
Figure 1.. Flowchart of selected works.
Figure 2.
Figure 2.. Western Ontario McMaster University Osteoarthritis (WOMAC global) - IA-HA versus IA-SS.
Figure 3.
Figure 3.. Decreased pain at rest (VAS) - IA-AH versus IA-SS.
Figure 4.
Figure 4.. Lequesne’s functional index from 26 to 52 weeks - IA-HA versus IA-SS.
Figure 5.
Figure 5.. WOMAC (functional subscale) - score decrease - IA-HA versus IA-SS.
Figure 6.
Figure 6.. WOMAC (pain subscale) - score decrease - IA-HA versus IA-SS.
Figure 7.
Figure 7.. Decreased walking pain (VAS) - IA-HA versus IA-SS.
Figure 8.
Figure 8.. Adverse events - IA-AH versus IA-SS.
Figure 9.
Figure 9.. WOMAC pain score (12 and 26 weeks) - IA-HA versus IA-SS.
Figure 10.
Figure 10.. Pain assessment - VAS (12 and 26 weeks) - IA-HA versus IA-SS.
Figure 11.
Figure 11.. Pain assessment - overall WOMAC (26 and 52 weeks) - IA-HA versus IA-SS.
Figure 12.
Figure 12.. Adverse events - IA-HA versus IA-SS.

References

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    1. Chevalier X, Jerosch J, Goupille P, Dijk N, Luyten FP, Scott DL, et al. Single, intra-articular treatment with 6 ml hylan G-F 20 in patients with symptomatic primary osteoarthritis of the knee: a randomised, multicentre, double-blind, placebo controlled trial. Ann Rheum Dis. 2010;69(1):113–119. doi: 10.1136/ard.2008.094623. - DOI - PMC - PubMed
    1. Day R, Brooks P, Conaghan PG, Petersen M, Multicenter Trial Crane A double blind, randomized, multicenter, parallel group study of the effectiveness and tolerance of intraarticular hyaluronan in osteoarthritis of the knee. J Rheumatol. 2004;31(4):775–782. - PubMed
    1. Dougados M, Nguyen M, Listrat V, Amor B. High molecular weight sodium hyaluronate (hyalectin) in osteoarthritis of the knee: a 1 year placebo-controlled trial. Osteoarthritis Cartilage. 1993;1(2):97–103. doi: 10.1016/s1063-4584(05)80024-x. - DOI - PubMed

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