Review

. 2023 Sep 26:11:1196596.

doi: 10.3389/fpubh.2023.1196596. eCollection 2023.

The promise of digital healthcare technologies

Andy Wai Kan Yeung^{1

2}, Ali Torkamani³, Atul J Butte^{4

5}, Benjamin S Glicksberg^{6

7}, Björn Schuller^{8

9}, Blanca Rodriguez¹⁰, Daniel S W Ting^{11

12}, David Bates¹³, Eva Schaden^{2

14}, Hanchuan Peng¹⁵, Harald Willschke^{2

14}, Jeroen van der Laak¹⁶, Josip Car^{17

18}, Kazem Rahimi¹⁹, Leo Anthony Celi^{20

21

22}, Maciej Banach^{23

24}, Maria Kletecka-Pulker^{2

25}, Oliver Kimberger^{2

14}, Roland Eils²⁶, Sheikh Mohammed Shariful Islam²⁷, Stephen T Wong^{28

29}, Tien Yin Wong^{11

12

30}, Wei Gao³¹, Søren Brunak³², Atanas G Atanasov^{2

33}

Affiliations

¹ Oral and Maxillofacial Radiology, Applied Oral Sciences and Community Dental Care, Faculty of Dentistry, University of Hong Kong, Hong Kong, China.
² Ludwig Boltzmann Institute Digital Health and Patient Safety, Medical University of Vienna, Vienna, Austria.
³ Department of Integrative Structural and Computational Biology, Scripps Research Translational Institute, La Jolla, CA, United States.
⁴ Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, United States.
⁵ Department of Pediatrics, University of California, San Francisco, San Francisco, CA, United States.
⁶ Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
⁷ Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
⁸ Department of Computing, Imperial College London, London, United Kingdom.
⁹ Chair of Embedded Intelligence for Health Care and Wellbeing, University of Augsburg, Augsburg, Germany.
¹⁰ Department of Computer Science, University of Oxford, Oxford, United Kingdom.
¹¹ Singapore National Eye Center, Singapore Eye Research Institute, Singapore, Singapore.
¹² Duke-NUS Medical School, National University of Singapore, Singapore, Singapore.
¹³ Department of General Internal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
¹⁴ Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Vienna, Austria.
¹⁵ Institute for Brain and Intelligence, Southeast University, Nanjing, China.
¹⁶ Department of Pathology, Radboud University Medical Center, Nijmegen, Netherlands.
¹⁷ Primary Care and Public Health, School of Public Health, Imperial College London, London, United Kingdom.
¹⁸ Centre for Population Health Sciences, LKC Medicine, Nanyang Technological University, Singapore, Singapore.
¹⁹ Deep Medicine Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom.
²⁰ Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, United States.
²¹ Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States.
²² Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
²³ Department of Preventive Cardiology and Lipidology, Medical University of Lodz (MUL), Lodz, Poland.
²⁴ Department of Cardiology and Adult Congenital Heart Diseases, Polish Mother's Memorial Hospital Research Institute (PMMHRI), Lodz, Poland.
²⁵ Institute for Ethics and Law in Medicine, University of Vienna, Vienna, Austria.
²⁶ Digital Health Center, Berlin Institute of Health (BIH), Charité - Universitätsmedizin Berlin, Berlin, Germany.
²⁷ Institute for Physical Activity and Nutrition, Deakin University, Geelong, VIC, Australia.
²⁸ Department of Systems Medicine and Bioengineering, Houston Methodist Cancer Center, T. T. and W. F. Chao Center for BRAIN, Houston Methodist Academic Institute, Houston Methodist Hospital, Houston, TX, United States.
²⁹ Departments of Radiology, Pathology and Laboratory Medicine and Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, United States.
³⁰ Tsinghua Medicine, Tsinghua University, Beijing, China.
³¹ Andrew and Peggy Cherng Department of Medical Engineering, California Institute of Technology, Pasadena, CA, United States.
³² Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
³³ Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, Jastrzebiec, Poland.

PMID: 37822534
PMCID: PMC10562722
DOI: 10.3389/fpubh.2023.1196596

Review

The promise of digital healthcare technologies

Andy Wai Kan Yeung et al. Front Public Health. 2023.

. 2023 Sep 26:11:1196596.

doi: 10.3389/fpubh.2023.1196596. eCollection 2023.

Authors

Affiliations

¹ Oral and Maxillofacial Radiology, Applied Oral Sciences and Community Dental Care, Faculty of Dentistry, University of Hong Kong, Hong Kong, China.
² Ludwig Boltzmann Institute Digital Health and Patient Safety, Medical University of Vienna, Vienna, Austria.
³ Department of Integrative Structural and Computational Biology, Scripps Research Translational Institute, La Jolla, CA, United States.
⁴ Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, United States.
⁵ Department of Pediatrics, University of California, San Francisco, San Francisco, CA, United States.
⁶ Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
⁷ Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
⁸ Department of Computing, Imperial College London, London, United Kingdom.
⁹ Chair of Embedded Intelligence for Health Care and Wellbeing, University of Augsburg, Augsburg, Germany.
¹⁰ Department of Computer Science, University of Oxford, Oxford, United Kingdom.
¹¹ Singapore National Eye Center, Singapore Eye Research Institute, Singapore, Singapore.
¹² Duke-NUS Medical School, National University of Singapore, Singapore, Singapore.
¹³ Department of General Internal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
¹⁴ Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Vienna, Austria.
¹⁵ Institute for Brain and Intelligence, Southeast University, Nanjing, China.
¹⁶ Department of Pathology, Radboud University Medical Center, Nijmegen, Netherlands.
¹⁷ Primary Care and Public Health, School of Public Health, Imperial College London, London, United Kingdom.
¹⁸ Centre for Population Health Sciences, LKC Medicine, Nanyang Technological University, Singapore, Singapore.
¹⁹ Deep Medicine Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom.
²⁰ Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, United States.
²¹ Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States.
²² Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
²³ Department of Preventive Cardiology and Lipidology, Medical University of Lodz (MUL), Lodz, Poland.
²⁴ Department of Cardiology and Adult Congenital Heart Diseases, Polish Mother's Memorial Hospital Research Institute (PMMHRI), Lodz, Poland.
²⁵ Institute for Ethics and Law in Medicine, University of Vienna, Vienna, Austria.
²⁶ Digital Health Center, Berlin Institute of Health (BIH), Charité - Universitätsmedizin Berlin, Berlin, Germany.
²⁷ Institute for Physical Activity and Nutrition, Deakin University, Geelong, VIC, Australia.
²⁸ Department of Systems Medicine and Bioengineering, Houston Methodist Cancer Center, T. T. and W. F. Chao Center for BRAIN, Houston Methodist Academic Institute, Houston Methodist Hospital, Houston, TX, United States.
²⁹ Departments of Radiology, Pathology and Laboratory Medicine and Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, United States.
³⁰ Tsinghua Medicine, Tsinghua University, Beijing, China.
³¹ Andrew and Peggy Cherng Department of Medical Engineering, California Institute of Technology, Pasadena, CA, United States.
³² Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
³³ Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, Jastrzebiec, Poland.

PMID: 37822534
PMCID: PMC10562722
DOI: 10.3389/fpubh.2023.1196596

Abstract

Digital health technologies have been in use for many years in a wide spectrum of healthcare scenarios. This narrative review outlines the current use and the future strategies and significance of digital health technologies in modern healthcare applications. It covers the current state of the scientific field (delineating major strengths, limitations, and applications) and envisions the future impact of relevant emerging key technologies. Furthermore, we attempt to provide recommendations for innovative approaches that would accelerate and benefit the research, translation and utilization of digital health technologies.

Keywords: bioinformatics; biosensors; digital health; precision medicine; telehealth.

Copyright © 2023 Yeung, Torkamani, Butte, Glicksberg, Schuller, Rodriguez, Ting, Bates, Schaden, Peng, Willschke, van der Laak, Car, Rahimi, Celi, Banach, Kletecka-Pulker, Kimberger, Eils, Islam, Wong, Wong, Gao, Brunak and Atanasov.

PubMed Disclaimer

Conflict of interest statement

Outside the submitted work SB reports ownerships in Intomics A/S, Hoba Therapeutics Aps, Novo Nordisk A/S, Lundbeck A/S, ALK abello A/S and managing board memberships in Proscion A/S and Intomics A/S. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

**Figure 1**
The integration of digital health technologies into the existing healthcare system requires input from various stakeholders. Partially based on Naik et al. (49).

**Figure 2**
Schematic diagram of GP and doctor training by digital health/AI/ML.

**Figure 3**
The interconnections between various components in digital health technologies.

**Figure 4**
The future trend of digital health technologies with virtual reality, genomics, or blockchain.

See this image and copyright information in PMC

References

1. World Health Organization (2021). Global strategy on digital health 2020–2025 [online]. Available at: https://apps.who.int/iris/bitstream/handle/10665/344249/9789240020924-en... (Accessed December 2, 2022).
1. Herold F, Theobald P, Gronwald T, Rapp MA, Müller NG. Going digital–a commentary on the terminology used at the intersection of physical activity and digital health. Eur Rev Aging Phys Act. (2022) 19:17. doi: 10.1186/s11556-022-00296-y, PMID: - DOI - PMC - PubMed
1. Kletečka-Pulker M, Völkl-Kernstock S, Fassl A, Klager E, Willschke H, Klomfar S, et al. Telehealth in times of COVID-19: spotlight on Austria. Healthcare. (2021) 9:280. doi: 10.3390/healthcare9030280, PMID: - DOI - PMC - PubMed
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1. Car J, Sheikh A. Telephone consultations. BMJ. (2003) 326:966–9. doi: 10.1136/bmj.326.7396.966, PMID: - DOI - PMC - PubMed

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The promise of digital healthcare technologies

Affiliations

The promise of digital healthcare technologies

Authors

Affiliations

Abstract

Conflict of interest statement

Figures

References

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Medical